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Biomedical subjects

L P Rodionova

Publications and source records attributed to L P Rodionova.

17 recordsLinked to original sources
PubMed1990

[The stimulating effect of helium-neon laser radiation on rabbit eyes].

Local and general reactions have been studied after subjecting a rabbit eye to dispersed helium-neon laser radiation, 8 x 10(-6) wt/cm-2, 10 min daily for 10 days. There were recorded increase of blood filling of the uveal tract of the eye, changes in the indices of systemic hemodynamics, systolic and diastolic pressure, stroke and minute volume of blood volume, activation of separate links of antioxidant system connected both with oxidation-reduction of thiol disulfide system and the functioning of antiperoxide enzymes. The activation of antioxidant system has a local character, the changes in the retina of the eye and pigmented epithelium is expressed stronger than in the peripheral blood. The results obtained speak about relationship between the stimulating effect of helium-neon laser radiation on the rabbit eye and activation of antioxidant system.

Animals↗
PubMed1989

[Sensitivity of animals to CO2 laser radiation].

The study was undertaken to analyze the state of visual, cardiovascular and antioxidant systems along with peripheral blood exposed to laser emission with the wavelength of 10.6 mm and energetic exposure equal to that of threshold (21 J.cm2) and subthreshold (1/7 of the threshold value). Not only local but also general changes were detected. The cardiovascular and antioxidant systems were most sensitive to this type of exposure. The degree of changes was dose-dependent.

Animals↗
PubMed1987

[Effect of unithiol and acetylcysteine on lipid peroxidation and the erythrocyte antioxidant system in sensitized guinea pigs].

The effect of unithiol and acetylcysteine on lipid peroxidation, thioldisulfide equilibrium, glucose-6-phosphate dehydrogenase, glutathione reductase and lactate dehydrogenase activity and on erythrocyte resistance was studied in guinea-pigs during sensitization with C. maltosa. Sensibilized animals receiving thiol antioxidants showed partial restoration of normal biochemical levels.

Acetylcysteine↗
PubMedDate not supplied

[Permissible level of laser radiation of wavelength 10.6 microns].

In a four-month experiment with 102 male rabbits and 42 HRS/U mice and 30 days after termination thereof, study was made of local and general response of an organism to the effect of laser radiation (10.6 microns wave length and energy exposition 1/7 of the threshold). The radiation tolerance level was estimated.

Animals↗
PubMedDate not supplied

[The role of the antioxidant system in the mechanism of adaptation to intensive noise].

It has been shown in the experiment with albino rats that the prolonged influence of stable noise (90 dB) results in a shift of the redox equilibrium in the thiol-disulphide and ascorbate systems of the adrenal gland and myocardium tissues towards oxidation and the activity of glucoso-6-phosphate dehydrogenase and superoxide dismutase decreases. A concept on the pathogenetic role of the redox equilibrium disturbance in the thiol-disulphide system, in particular, in the development of noise pathology is suggested.

Adaptation, Physiological↗
PubMedDate not supplied

[The antioxidant system in noise-induced stress].

Some patterns of the antioxidant system were altered in rat blood and tissues after treatment with noise of 90 dB. Phase alterations were found in content of SH- and SS-groups, in ascorbate-dependent redox balance as well as in activity of glutathione reductase, glucose-6-phosphate- and lactate dehydrogenases. These data suggest that the antioxidant system is of importance in the adaptation reactions. Administration of antioxidant drugs (unitol, ascorbic acid and tocopherol) normalized the antioxidant drugs (unitol, ascorbic acid and tocopherol) normalized the antioxidant system patterns studied. These drugs could be used to enhance the nonspecific body resistance to noise stress.

Adaptation, Physiological↗