PubMed Health⌕ Search

Biomedical subjects

L Paim

Publications and source records attributed to L Paim.

6 recordsLinked to original sources
PubMed1999

Lectin-induced nitric oxide production.

Considering that nitric oxide (NO) may be involved in anti-tumoral and anti-parasite lectin effects, in this report we investigated whether lectin induces NO production. Lectins from Canavalia brasiliensis, Dioclea grandiflora, Pisum arvense (PAA), and concanavalin A induced murine peritoneal cells to produce NO in vitro. PAA induced similar levels to that obtained with lipopolysaccharide plus interferon-gamma. NO production by adherent cells was significantly lower than that of unfractionated cells, suggesting a combination of lectin stimuli directly on macrophages and via lymphocyte stimulation. Ex vivo experiments showed that cells stimulated in vivo could maintain NO production in vitro without further stimuli. NO synthesis blockage in vivo can significantly increase cell numbers in draining lymph nodes after lectin injection compared to unblocked controls, suggesting an in vivo association of lectin stimuli and NO production. Taken together these data show that lectins can induce NO production both in vitro and in vivo.

Animals↗
PubMed1992

[Is nursing a science or a profession?].

Traditionally, human knowledge has been considered in the context of disciplines which can be divided in two groups: Academics and professionals. The aim of academic disciplines is the knowledge and their theories are descriptive in nature. For this reason they are named science. In contrast, professional disciplines are move comprehensive, directed toward practical aims and there is a need to and to work. Nursing as a professional discipline has been influenced by four school of thought named; service, administration, academic and practice. Currently the nursing practice is developed based on three different theoretic and philosophic branches.

Brazil↗
PubMedDate not supplied

[Nursing training in Brazil in the 1970's].

The objective of this study is to revisit the period of time between 1975 and 1979, and, within it, the history of the implantation of nursing graduation courses in federal universities and in geo-educational districts. It presents the development of a project called Projeto de Enfermagem no Grupo Setorial de Saúde--(Nursing Project in Health) SESU/DAU/MEC (ministry of culture and education), and points out the social and political determinants of the, so planned, qualitative and quantitative development of the courses mentioned before. The research clarifies the proposal, process and accomplishments of the Superior Nursing Project of Education, which was predominantly private until 1974 and became predominantly public from 1976 on. Furthermore, it also indicates implications such as: the Commission of Nursing Education Specialists (CEEEnfermagem), which was linked to ABEn and was the first collective proposal of Areas and Lines of Research in Nursing (CNPq/CAPES/DAU/ABEn); as well as the introduction of institutionalized study fields in the academic institutions.

Brazil↗