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L Paradowski

Publications and source records attributed to L Paradowski.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Non-ulcer dyspepsia.

During the last decade a new disease entity numbered among functional disorders of the digestive tract and defined as "non-ulcer dyspepsia", has been isolated. This disease is diagnosed most frequently at the age of 20 to 40 years. In West-European countries it is diagnosed in about 30% of out patients. Symptomatology of the disease is very ample and is, after exclusion of organic diseases of the digestive tract, the basis of diagnosis and classification. Present knowledge on the pathophysiology of "non-ulcer dyspepsia" is incomplete and based mainly on study results of the motility of the stomach and small intestine under manometric examination. In spite of that one attains satisfactory therapeutical effects during a prolonged administration of prokinetic drugs (dopamine receptor antagonists and peripheral parasympathomimetics).

Dyspepsia↗
PubMedDate not supplied

Esophageal motility in the personnel operating heavy self-propelled mining machines.

We examined 47 men exposed to whole-body vibration for a long time (average 9.8 years) and tested esophageal motility. The following parameters were measured: mean pressure in the body of esophagus during the passing of peristaltic wave, maximum value of pressure during the passing of peristaltic wave, mean and maximum duration of spasm and peristaltic wave transmission velocity was calculated. In over 1/4 exposed to whole-body vibration disorders of esophagus motility were observed. These disorders are probably a consequence of vocational exposure to whole-body vibration.

Adult↗
PubMedDate not supplied

The effect of PGF2 alpha-estrumate on the secretion and composition of abomasal juice in sheep during H2-histaminic receptor blockade with cimetidine.

The effect of PGF2 alpha was investigated on the secretion of abomasal juice in sheep after blockade of the H2-histaminic receptor with intravenous cimetidine (150-200 mg). Cimetidine inhibited abomasal juice secretion diminishing juice volume and the content of acid and pepsin in it. During this inhibition intramuscular injection of PGF2 alpha 2.0-4.0 micrograms/kg of body weight caused an increase of these parameters. In control experiments histamine administered (23-28 micrograms/kg) after cimetidine failed to increase the secretion of abomasal juice confirming thus complete blockade of the H2-histaminic receptor. The obtained results demonstrated that the stimulating effect of PGF2 alpha on abomasal juice secretion was not mediated by the H2-histaminic receptor.

Abomasum↗
PubMedDate not supplied

[Ulcerative colitis and pregnancy].

On the basis of literature and on the grounds of their own experience the authors presented their opinions on the coexistence of colitis ulcerosa (c.u.) and pregnancy. It was stressed that colitis ulcerosa does not decrease fertility in women whereas the taking of salazosulfapyridine diminishes fertility in men. Pregnancy should be planned during the remission period. Successive pregnancies in the same patient with coexistent c.u. should be taken individually. Classic pharmacotherapy end endoscopic diagnostics are not contraindicated in pregnancy. Past operation (e.g. partial or total colectomy) do not decrease chances of giving birth to a child. There is no evidence that artificial abortion exerts a favourable influence on the course of colitis ulcerosa. Cesarean section should be performed of obstetrical indications only. In addition, the authors emphasize the necessity of a strict monitoring of c.u. in the first trimester of pregnancy and during puerperium, as well as of a rigorous gynecological supervision in the third trimester of pregnancy.

Colitis, Ulcerative↗