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L Parmeggiani

Publications and source records attributed to L Parmeggiani.

At least 19 recordsLinked to original sources
PubMed1992

Slowly progressive familial dementia with recurrent strokes and white matter hypodensities on CT scan.

We describe 2 normotensive sisters presenting slowly progressive dementia associated with acute or subacute focal neurological symptoms, unilateral or bilateral motor signs, and dysarthria. Their father, who died in the seventh decade, had a similar clinical picture. Computerized axial tomography (CT) scan of the head showed symmetrical hypodensities in the periventricular white matter and mild to moderate hydrocephalus. In these patients a diagnosis of Binswanger's disease was based on the clinical features supported by white matter changes on CT scan. Our study suggests that genetic factors may play a role in the etiology of Binswanger's disease.

Adult↗
PubMed1989

Caudal migration of the Günther vena caval filter.

Two cases of downward migration of the Günther vena caval filter are reported. Migration resulted in recurrent pulmonary embolism in one case; in the second, partial thrombosis of the filter precluded retrieval. Both patients were treated successfully by placement of a second Günther filter in the infrarenal vena cava. Until more experience with this filter is available, the authors recommend use of the 30-mm filter in medium- and large-size venae cavae. Radiographs should be obtained to check the position of the filter immediately and 1 week after placement. In addition anticoagulative therapy should be continued whenever possible.

Aged↗
PubMed1987

Alpha interferon in the treatment of symptomatic myelofibrosis with myeloid metaplasia.

2 patients with myelofibrosis and myeloid metaplasia had symptomatic splenomegaly and were treated with interferon alpha-2c (IFN alpha-2c). The splenic pain and pressure symptoms disappeared, accompanied by a decrease in the size of the spleen. However, the peripheral blood count worsened and no improvement in the bone marrow fibrosis could be observed.

Humans↗
PubMed1984

[Aggressive therapy in a case of Moschowitz syndrome].

We report a case of thrombotic thrombocytopenic purpura which responded spectacularly to therapy consisting of corticosteroids, prostacyclin, high doses of platelet anti-aggregants and repeated plasma exchange. There was no anomaly of the von Willebrand factor VIII. The number of schizocytes and the lactate dehydrogenase level are as important as the beta-thromboglobulin dosage.

Adrenal Cortex Hormones↗
PubMed1984

[1:1 atrial flutter in an elderly patient: one of the methods of discovering Wolff-Parkinson-White syndrome. Apropos of a case in an adult].

Atrial flutter with 1:1 atrioventricular conduction giving rise to a ventricular rhythm of 240/min in an 80 year old man was the first sign of the Wolff-Parkinson-White syndrome; all previous electrocardiogrammes had shown no evidence of pre-excitation. It was only on the fifth day of hospitalisation that the ECG showed a short PR interval with a delta wave. This case illustrates that: --all supraventricular arrhythmias with abnormally high ventricular rates (over 220/min in adults) should alert to the possibility of an accessory atrioventricular pathway; --rapid atrioventricular conduction may be the first sign of an accessory pathway; --the differential diagnosis lies between an accessory atrioventricular pathway and an atriohisian tract; --digitalis, which may shorten the refractory period of the accessory pathway, is contraindicated in patients with a Kent bundle.

Aged↗
PubMedDate not supplied

Liver system. V. Activation-extinction line of cyclic hepatocyte activities.

The excitation-extintion line of hepatocytes from an inert state towards the stabilization of a given activity is described. Within the cell, the switching on of any given activity is a competitive process among different activities. The process is driven by the influence field created in the environment of the Rappaport acinus by sinusoidal blood which changes its characteristics during its passage from the portal zone to the central vein. Every step of the excitation-extintion pathway follows the so-called law of autoisodiasostasis (AIS), i.e. it is characterized by an oscillatory motion between restoring (homopoiesis or HP) and working (homeorhesis or HR) states. Since the cyclical bistable equilibrium of AIS characterizes all conditions of hepatocyte activities, the AIS cycle can be defined a limit cycle.

Humans↗