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Biomedical subjects

L Pendefunda

Publications and source records attributed to L Pendefunda.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[The transient ischemic attack, between diagnosis and treatment].

The transient ischemic attack (TIA) in cerebral circulation in 161 patients is studied. The causes and favouring factors are analysed, arterial hypertension and dyslipidemias representing 70% of the factors that might be incriminated in the physiopathology of TIAs. The paraclinical and therapeutic results demonstrate that in over 30% of the cases the etiology could be explained by "the multiple defect theory", the importance of transcranial Doppler in the diagnosis and prognosis of TIA, especially in the young patients, being underlined.

Age Distribution↗
PubMedDate not supplied

Drug test value by transcranial Doppler in the diagnosis of neurologic vascular diseases.

The response to various drugs was studied in relation to intracranial vascularization under ultrasound control. The investigation was made in 461 patients (258 females and 203 males) aged between 18 and 87 years. Vasoactive substances interacting with the synaptic neurotransmitters metabolism directly or via CNS were used: papaverine, vincamine, sadamin, nicergoline, carbocromen, clonidine, captopril, magnesium sulphate, nifedipine, piracetam, nicotine, caffeine, dipyridamole, histamine, fentanyl. The normal arterial response was compared with the response of the involved atherosclerotic artery or with congenital malformation. The tests value in the diagnosis of neurologic vascular diseases is discussed.

Adolescent↗
PubMedDate not supplied

Assessment of hemodynamic disturbances in aphasic patients by transcranial Doppler ultrasonography.

The author presents a study of Doppler cerebrovascular ultrasonography carried out in 38 aphasie patients (forms ranging from transient speech disturbances to severe, persistent disturbances of motor, sensory or mixed aphasia) after ischemic or hemorrhagic stroke. In these cases, the clinical symptoms were dominated by speech impairment and neurological deficits (mainly pyramidal), of low intensity or transient. The angiographic study revealed stenotic or occlusive disturbances at various levels of the cerebral arterial trunks. The prevalence of some clinical aspects of aphasia correlated with Doppler velocimetric images is discussed and the use of transcranial Doppler method in idiopathic aphasia, possible consequence of a transient ischemic attack, is suggested.

Adult↗
PubMedDate not supplied

[Neurosonography reveals various etiologies of migraine].

125 patients with migraine were studied by determining the intracerebral blood flow by means of Doppler cranial neurosonography. The findings confirm the presence of certain nonsystematic vascular defects involved in the pathologic response of the synaptic factors of the cerebral blood flow, thus demonstrating the validity of the multiple pathologic arterial segments and the possibility of response to various therapies. The study classifies migraines based on Doppler cerebrovascular neurosonography.

Cerebral Arterial Diseases↗
PubMedDate not supplied

[Changes in the pulsatility index (Gosling) under drug action].

The alterations in cerebral hemodynamics induced by drugs (papaverine, Cavinton, magnesium sulphate, piracetam, histamine) in a series of 152 patients compared with a control series were analysed. The response of each basal cerebral artery to these drugs is assessed through the pulsatility index value.

Blood Flow Velocity↗
PubMedDate not supplied

[Transcranial Doppler exploration of the brain stem vascularization in neurological pathology].

The hemodynamic alterations in the vertebrobasilar system arteries of 1051 patients are discussed. The aspects revealed by transcranial Doppler are classified as obstructions, stenoses and atherosclerotic type lesions. Their prevalence compared with the clinical diagnosis or through other investigation methods is commented upon, an etiological classification of such alterations in hemodynamics in the basilar and vertebral arteries being attempted. Multiple defect theory seems to be, in such cases as well, the clinical expression accounting for the pathogenic phenomena and response to drug tests.

Adolescent↗
PubMedDate not supplied

[Intracerebral hemodynamic changes in lesions of the internal carotid arteries].

The Doppler transcranial sonography is useful in making a correct, functional diagnosis of cerebral hemodynamics in the case of internal carotid artery lesions. Being a noninvasive method, it can be employed in following up the evolution of a stenosis, for assessing the collateral blood supply in the territory of the obstructed artery branches and thus for determining the prognosis of a cerebral infarction. For an adequate prophylactic and curative treatment the method is recommended, alone, in estimating the extra and intracranial circulation.

Adult↗