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Biomedical subjects

L Pettijohn

Publications and source records attributed to L Pettijohn.

2 recordsLinked to original sources

Mood and carbohydrate cravings.

The relationship between mood and carbohydrate cravings, and the possible role of gender in these associations, was investigated in a sample of 113 males and 138 female college students. Participants completed a Cravings Questionnaire and several mood inventories (profile of mood states, Beck Depression Inventory, and the Vitality Inventory) in groups of 25. Individuals classifying themselves as "carbohydrate cravers" reported foods rich in carbohydrates, and "protein cravers" reported protein-rich foods as being the ones they most strongly craved. Carbohydrate cravers reported feeling distressed prior to their cravings and satisfied, happy/good and relaxed following carbohydrate consumption. Protein cravers reported feeling anxious or hungry prior to their cravings and happy, normal, bored, and energetic following protein-rich food consumption. A non-significant correlation existed between "protein" cravers' ratings of craving intensity and mood, but a significant positive correlation existed between "carbohydrate" cravers' ratings of craving intensity and almost all mood scales assessed for both male and female "carbohydrate" cravers. The correlation between craving intensity and mood existed predominately with individuals who craved sweet carbohydrate-rich foods.

Adolescent↗

Lack of linkage of apparently dominant cleft lip (palate) to two candidate chromosomal regions.

Two regions were chosen for linkage studies to cleft lip with or without cleft palate (CL[P]) because they are break points of a balanced translocation in a patient with severe bilateral facial clefting. We used dinucleotide repeats to test chromosomal regions 1q21 and 22q11.2 for such linkage. We studied three families with apparently dominantly inherited CL(P). Families #1 and #2 are local Caucasian families that have not been previously reported; family #3 is a Belgian family that has been previously published [DePaepe, 1989]. Significant evidence against close linkage of the dinucleotide repeats (D1S104, D22S156, D22S264) with CL(P) using a dominant model was obtained. Three other candidate regions were tested (2q37,4q31, and 8p) with the dinucleotide repeats PAX3, D4S175, and LPL respectively. The LOD scores generated at these three loci are not statistically significant for demonstrating negative linkage at these regions. However, they may be used with other informative families in the future, since LOD scores for the same model of inheritance may be added together. Negative or neutral LOD scores were generated at all informative loci using an autosomal dominant model with decreased penetrance.

Base Sequence↗