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Biomedical subjects

L Picon

Publications and source records attributed to L Picon.

97 records · Page 6Linked to original sources
PubMedDate not supplied

[Toxoplasmic pleuro-pericarditis associated with Hodgkin's disease].

Pericarditis caused by toxoplasma infection is exceptional: 16 cases only have been published since 1943. The authors report a case of Hodgkin's disease associated with, and revealed by, toxoplasmic pleuro-pericarditis, and they review the literature on this complication of toxoplasmosis. Since the infection can be cured and since pericarditis may become chronic and constrictive if untreated, toxoplasmosis should be envisaged and confirmed or infirmed by serological tests in all patients presenting with pericarditis of uncertain origin. Provided it has not reached the chronic stage, toxoplasmic pericarditis responds well to the conventional treatment with pyrimethamine and sulfonamides.

Adolescent↗
PubMedDate not supplied

Effects of counterregulatory hormones on insulin-induced glucose utilization by individual tissues in rats.

The effect of counterregulatory hormones (epinephrine, norepinephrine and glucocorticoids) on insulin-induced glucose utilization in individual tissues of normal rats was investigated in vivo. This was done in normoglycaemic conditions, using the euglycaemic hyperinsulinaemic clamp combined with an injection of 2-[1-3H]-deoxyglucose. The main effect of these hormones was to reduce insulin-induced glucose utilization in skeletal muscles and particularly in the oxidative one. No changes were observed in heart diaphragm and adipose tissues. These results emphazise the role of counterregulatory hormones on glucose utilization and demonstrate that muscles are their major site of action. They support the notion that the increase in plasma concentrations of these hormones could play a role in states of insulin resistance like obesity and diabetes.

Adipose Tissue↗
PubMedDate not supplied

[Hepatic artery ligation for liver metastasis of a acinar cell carcinoma of the pancreas revealed by a nodular panniculitis].

We report the case of a 67-year-old-man presenting with pancreatic acinar cell carcinoma revealed by dermatological manifestations of cytosteatonecrosis and treated by hepatic artery ligation. The pancreatic etiology of these lesions was suspected due to hyperlipasemia, and was confirmed by abdominal computerized tomography showing a pancreatic tumor and multiple liver nodules, and by histological examination of one of these lesions. Because of symptomatic treatment failure, rapid impairment of patient's general condition, and by analogy with the treatment of hepatic metastases of neuroendocrine tumors, hepatic artery ligation was performed. Lipasemia decreased markedly and symptoms disappeared for 45 days. Hepatic artery obstruction may be used for emergency treatment of secreting liver metastases.

Aged↗