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Biomedical subjects

L Pilo

Publications and source records attributed to L Pilo.

5 recordsLinked to original sources

Possibility of observable amount of gravitational waves from inflation.

The curvaton and inhomogeneous reheating scenarios for the generation of the cosmological curvature perturbation on large scales represent an alternative to the standard slow-roll scenario. The basic assumption of these mechanisms is that the initial curvature perturbation due to the inflaton field is negligible. This is usually attained by lowering the energy scale of inflation, thereby concluding that the amount of gravitational waves produced during inflation is highly suppressed. We show that the curvaton and inhomogeneous reheating scenarios are compatible with a level of gravity-wave fluctuations which may well be observed in future satellite experiments.

Journal Article↗

Depression in multiple system atrophy and in idiopathic Parkinson's disease: a pilot comparative study.

Multiple system atrophy (MSA) is a disease causing parkinsonism in which response to levodopa is classically absent, poor, or transient. Idiopathic Parkinson's disease (IPD) itself, which responds favorably to levodopa, has been associated with the development of disease-related depression. Over and above the clinical and pathological characteristics of IPD, MSA causes additional, more widespread, clinical and pathological deficits. We have compared motor disability and mood in 12 patients with MSA and 12 with IPD. There was more severe motor disability, but no clinical evidence of depression among the MSA patients studied, and their Beck Depression Inventory scores did not differ significantly from the group with IPD. We conclude that depression does not appear to be more common in MSA than in IPD.

Activities of Daily Living↗

The psychiatric complications of epilepsy.

The psychiatric complications of epilepsy are varied but may be considered under two main groups--those directly related to ictal activity and those that occur during the inter-ictal period. Epilepsy and psychiatry are also similar in that they cause a great deal of social difficulties and restriction in terms of activities and employment opportunities because of the associated stigma and prejudice. The various complications are discussed and illustrated with case studies where appropriate.

Adult↗

Neuroleptic malignant syndrome in organic brain disease and physical illness.

The neuroleptic malignant syndrome is a serious complication associated with the use of antipsychotic drugs that has received a great deal of interest in recent times. Although its aetiology has not been fully understood, it often occurs in association with underlying brain disease and physical debilitation. Two such cases are described. The various hypotheses concerning the aetiology and pathogenesis of this condition are also discussed.

Adult↗

Gelastic epilepsy--a case report.

Gelastic epilepsy is an uncommon phenomenon and it is particularly uncommon in adults. This paper describes a case of gelastic epilepsy in a middle-aged woman presented in a psychiatric hospital. A short history of the condition, clinical and electroencephalographic findings in gelastic epilepsy and causes of pathological laughter are discussed.

Epilepsy↗