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Biomedical subjects

L Polyák

Publications and source records attributed to L Polyák.

14 recordsLinked to original sources

[Adjuvant BCG immunotherapy in the management of superficial bladder tumors].

The net benefit of BCG immunotherapeutic prophylactic effect on recurrence of superficial bladder tumours was investigated. The BCG treatment group consisted of 121 stage Ta, T1 patients, while the control group, 49 patients, was treated only with transurethral resection. During 3-year follow-up recurrence rate in the control group was 55.1%, while in the BCG group in the two-and-a-half-year follow-up it was 23.9%. The yearly repeated 6-week cycles resulted in decrease of recurrence rate to 11.8%. The recurrence indexes were 2.2 and 0.6 in the control group and in the repeated treatment group respectively. A progression rate of 18.8% was recorded in the control group and 4.1% in the treatment group. Finally both clinical and investigative results were summarised and the necessity of repeated immunotherapeutic BCG courses were emphasized.

BCG Vaccine↗

Long-term BCG immune therapy of superficial bladder tumours.

Long-term local BCG treatment of superficial bladder tumours is described and the 5-year results are reviewed. Complications of major significance in the course of immune therapy did not occur, loss due to death was not recorded. PPD skin test failed to furnish extra information regarding the biologic behaviour of the tumour. Annual repeats of the therapy promise better results than one single 6-week course.

Administration, Intravesical↗

A new approach to the treatment of polycystic kidneys.

Maximum conservativism was the watchword up to 1979 in dealing with polycystic disease. In the period 1979 to 1985 a total of 45 patients were subjected to 80 instances of polycystic resection whereby larger cysts were removed by excision, smaller ones by ignipuncture, with particular attention to extirpation of the perihilar cysts. Post-operative incidence of hypertension dropped from 33 to 3%. The method described is rated as one of the feasible expedients to deal with polycystic disease in the early compensated stage.

Adult↗

Urological tuberculosis mimicking bladder tumour.

A total of 8 patients have been treated in the recent 10 years in whom urogenital tuberculosis simulated the picture of bladder tumour. This occurred in 3% of overall patients with urogenital tuberculosis, i.e. primary diagnosis proved to be erroneous in such percentage of them. The course of the disease of 2 patients is reviewed in detail. In order to establish the differential diagnosis between the two diseases, the importance of bladder biopsy following polycystography is pointed out.

Adult↗

Organ-preserving surgery in kidney tumours.

After a survey of the international literature on organ-preserving surgery in kidney tumours, a surgical material of 12 cases is presented, in which a mean survival of 51 months has been attained. In similar cases medical treatment gave survivals of 7 months only. The factors affecting the survivals are analysed and resection in stage T1-2 is advocated on these grounds. Organ-preserving surgery is regarded as justified in stage T1N0M0, even if the other kidney is intact. The decisive importance of appropriate selection of the patients and of a meticulous surgical technique is emphasized.

Adenocarcinoma↗

Two cases of traumatic denudation of the penile and scrotal skin.

Two cases of denudation injuries of the penis and the scrotum are reviewed. In the first case a total skin erosion of the penis and scrotum has happened. In the second injury, the major part of the skin was lost. The reconstructive operations are shown in a series of photographs. Replacement of the total skin deficiency was performed by placing a split-thickness graft on the penis, while reconstruction of the scrotum was carried out by using a thigh pedicle flap. In the second case partial loss of the skin could be replaced by mobilizing the free skin edges.

Accidents, Occupational↗

[Primary carcinomas of the scrotum--5 cases].

Etiology, diagnostic difficulties and clinical feature of the scrotal carcinomata are described. In the course of 10 years 5 cases were observed. The patients at stage T3N2M0-1 survived still 4 to 8 months after operation, while the patients at stage T1 are all still alive. The significance of the early diagnosis is emphasized, in order to prolong the survival time.

Aged↗

Primary retroperitoneal tumours and cysts.

The authors give a summarizing report on retroperitoneal tumours and cysts. They review the origin and classification of tumours and cysts, their diagnostic and differential diagnostic possibilities as well as the therapeutic measures. Finally, their own 3 cases are reported.

Adult↗

Combined use of transurethral resection and needle biopsy in the diagnostics of carcinoma of the prostate.

On suspicion of prostatic tumour, the authors performed a combination of transurethral resection and needle biopsy to form a safe histological diagnosis as well as to apply an adequate therapy. Transurethral resection combined with needle biopsy is to be performed if patients present with dysuric complaints, and if tumour can be suspected on rectal palpation or based on the clinical picture. This intervention ensures an unequivocal diagnosis and eliminates the urinary obstruction. They also dealt with cases, in which only needle biopsy or transurethral resection could help in forming the correct diagnosis.

Adenoma↗

Primary ureteral tumours.

The authors report on the clinical picture, diagnostics and therapy of ureteral tumours in 4 patients. The most important symptoms are haematuria and pain. Of the diagnostic possibilities retrograde ureterography is the most significant. Their own surgical solution was ureteronephrectomy with excision of the orifice. Also the conservative therapeutic measures were surveyed. The post-operative control for detecting early recurrences is considered important.

Carcinoma, Transitional Cell↗

[Transurethral resection in bladder tumors].

The experience gained in the course of 127 transurethral resections of bladder tumours are described. After discussing the indications and the technique the authors present their own results. The advantages of transurethral resection are emphasized: reduced operational stress, early mobilization, quick removal of the catheter, few postoperative complications, low cost of nursing. Therefore the operation is given preference mainly in the treatment of elderly patients with bladder tumour.

Adult↗