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L Poulsgård

Publications and source records attributed to L Poulsgård.

10 recordsLinked to original sources

Sequentially evolved bilateral epidural haematomas.

Sequentially evolved bilateral epidural haematomas, where the second haematoma evolves after surgical removal of the first haematoma, are rarely reported. We report two cases of this entity. One patient was involved in a road traffic accident and the other was suffering from a head injury after an assault. CT scans showed that both patients had an unilateral epidural haematoma with a thin presumably epidural haemorrhage on the opposite side. Both patients were operated for their epidural haematomas, but did not improve after surgical treatment, and postoperative CT scans revealed evolving of an epidural haematoma on the opposite side. After evacuation of the second epidural haematoma both patients recovered quickly. Sequentially evolved bilateral epidural haematomas are rare, but must be considered in the postoperative intensive care treatment in patients with epidural haematomas. Both cases emphasize the need for intensive care monitoring after an operation for an epidural haematoma and the need for CT scans if the patient does not improve quickly after removal of the haematoma. This is especially important if a small contralateral haematoma is seen on the initial CT scan.

Adult↗

[Endoscopic closure of cranionasal cerebrospinal fluid fistulas with the use of neuronavigation--"Computer Aided Surgery"].

INTRODUCTION: Conventionally, cranionasal cerebrospinal fluid (CSF) fistulas have been closed by repair of the dural defect via an open craniotomy. These techniques may be cumbersome, not without complications, and far from successful. In recent years, endoscopic techniques have been developed in the field of nasal surgery and neurosurgery. Furthermore, by means of computer-aided surgery or neuronavigation, it is possible to identify the surgical track with a high degree of accuracy and, by the same token, identify the defect in the cranium. METHOD: By combining the endoscopic technique with computer-aided surgery, we have operated on six patients with cranionasal CSF fistulas endonasally. The fistula was confirmed before surgery by subaracnoidal injection of fluorescein. RESULTS: The surgery was successful and without any complications in all six cases. DISCUSSION: The method is recommended as the operation of first choice for cranionasal CFS fistulas, as compared to transcranial surgery. It is probably more efficient and with fewer complications than conventional surgery. A collaboration between neurosurgeons and ENT surgeons, like ours, can be recommended.

Adult↗

[Surgical treatment of carotid-cavernous fistulas. A description of open surgical techniques in the treatment of carotid-cavernous fistula with preserved normal flow in the internal carotid artery].

We have used a packing technique for surgical treatment of carotico-cavernous fistulas, which allows preservation of the flow in the internal carotid artery. We have treated six patients for carotico-cavernous fistulas with this technique, and in all patients the preoperative symptoms and signs disappeared completely. One patient still had a slight paresis of the left abducent nerve due to the operation three months after the operation. Surgical treatment of carotico-cavernous fistulas is effective and probably preserves the flow in the internal carotid artery.

Adult↗

[Results of treatment of meningitis during a 10-year period].

A review of 131 cases of purulent meningitis is presented. The patients are mainly non-pediatric and, because of that, meningitis caused by Streptococcus pneumoniae predominates. This is the main reason for the high overall mortality of 15.6%. The main etiological cause of lethal meningitis was Streptococcus pneumoniae, and it is discussed whether chloramphenicol, previously shown to exert an antagonistic effect on beta-lactam antibiotics, contributes to the relatively high mortality. It is suggested that chloramphenicol should be withdrawn from meningitis treatment and replaced by cefuroxime.

Adult↗

Rubidium uptake of mononuclear leukocytes from normotensive and borderline hypertensive first degree relatives to patients with essential hypertension.

Uptake of 86Rubidium of mononuclear leukocytes (MNL) was used as a measure of cellular sodium-potassium pump activity. 86Rb-uptake was determined with the pump stimulated mainly from inside the cells by sodium as well as with a combined stimulation from inside by sodium and from outside by Rb. In the first case there was an increased pump activity in MNL from borderline hypertensive offspring of hypertensive patients (BHO), and this may be related to an increased number of pump sites observed previously (10). Estimation of maximal pump activity (Vmax) of MNL suggested that Vmax of each pump site in MNL from BHO may be decreased compared to control value of MNL from healthy normotensive subjects.

Humans↗

Cytogenetic studies of 11 meningiomas and their clinical significance. II.

Cytogenetic analyses of 11 consecutive cases of meningiomas from 7 female and 4 male patients are reported. Chromosomal abnormalities were found in all cases. Only two of the cases showed cells with normal karyotype in addition to the abnormal stemline. Two of the cases displayed a more aggressive growth pattern than is usually seen in meningiomas. The first case was characterized by tumor invasion into the bone, a stemline with monosomy 22 and a hyperhaploid sideline. The second case was characterized by recurrency and a hypodiploid stemline. Extended clonal evolution was observed in one case.

Adult↗

Cytogenetic studies of 19 meningiomas and their clinical significance. I.

Cytogenetic analysis of 19 meningiomas from 10 female and 9 male patients are reported. Chromosomal abnormalities were found in all cases with a stemline karyotype 45, XY, -22 or 45, XX, -22. Three of these had additional sidelines: (a) 44, XX, -1, -4, -6, -8, -22, +19, +del(1) (:p33----q43), +dup(1) (p24----q31) t(1;1) (pter----p33::ter): (b) 44, X, -9, -14, -22, -X, +4, +del(X) (pter----q26), and (c) 44, XY, -19, -22, respectively.

Adult↗