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Biomedical subjects

L Press

Publications and source records attributed to L Press.

11 recordsLinked to original sources
PubMed1994

Clinical evaluation of Purilens, an ultraviolet light contact lens care system.

Purilens is a new contact lens care system that uses ultraviolet light and subsonic turbulence for lens cleaning and disinfection. In a single hands-off process using only preservative-free sterile saline, the lenses are ready to wear after a 15-minute cycle. This study was designed to test the safety of this contact lens care system. A total of 84 contact lens wearers from six centers were enrolled in the 3-month study, which comprised an initial visit and follow-up visits at 1, 2, 4, 8, and 12 weeks. At the end of the study, lenses and units were collected and a questionnaire was completed. Seventy-six of the 84 subjects (168 eyes) completed the study. No severe eye complications were reported, and no patients were removed from the study because of ocular problems or complications associated with the device or its use. Four patients were removed from the study for noncompliance with follow-up. Another four patients were active for 2 months, but were requested by the sponsor to complete the study 1 month early to complete data collection. Patient satisfaction was high. The study suggests that Purilens may be considered as an alternative for contact lens cleaning and disinfection.

Adolescent↗
PubMed1992

Attributes of tinnitus that may predict temporomandibular joint dysfunction.

A collection of 1002 patients with severe tinnitus, drawn from the Tinnitus Data Registry, were retrospectively surveyed to determine which traits or attributes of tinnitus could indicate the possibility of temporomandibular joint dysfunction (TMD) as the cause of tinnitus. The patients were divided into two groups: (1) a TMD group, consisting of 69 patients for whom there was no known cause of tinnitus except for one or more temporomandibular joint (TMJ) indicators, and (2) a comparison group with mixed etiologies (n = 860). Seventy-three patients were eliminated due to excessive complications relating to cause. The two groups were compared seeking those attributes of tinnitus that significantly separated them. No single benchmark standard was discovered that exclusively indicated tinnitus from TMJ origins. However, a total of 10 "TMJ Indicators" were discovered. The data for each of these indicators is presented and discussed. In addition, the attributes that did not significantly separate the two groups are listed. The study concludes with a recommendation for TMJ referral for those tinnitus patients with unknown etiology who demonstrate any three or more of the TMJ indicators.

Chi-Square Distribution↗
PubMed1989

Single-dose antibiotic prophylaxis in contaminated abdominal surgery.

Although perioperative antibiotic cover reduces the incidence of septic complications associated with abdominal surgery, the optimum duration of antibiotic exposure is open to question. This clinical trial compared the efficacy of a single dose of moxalactam (1 g intravenously) with an extended course of moxalactam (1 g intravenously for eight doses) in 1027 patients undergoing contaminated abdominal surgery. The wound infection rate was 5.4% (28/519) for the single-dose schedule and 6.1% (31/508) for the extended-cover regimen (the respective 95% confidence intervals being 3.6% to 7.7% and 4.2% to 8.6%). Over 80% of all patients undergoing abdominal surgery during the period of study were entered into the trial. There was no significant difference in the incidence of other complications between the two groups under study. It is concluded that a single dose of moxalactam is as effective as a 48-hour course when attempting to prevent infection after contaminated abdominal surgery.

Biliary Tract Surgical Procedures↗
PubMedDate not supplied

Attributes of tinnitus and the acceptance of masking.

Various characteristics of tinnitus were surveyed to determine whether they were associated with the acceptance of masking, which is used as a relief procedure for tinnitus. The characteristics considered were duration, loudness match, minimum masking level, and residual inhibition. Data for the characteristics of tinnitus were obtained from the Tinnitus Data Registry at the Oregon Hearing Research Center, which contains information on 784 tinnitus patients. The acceptance of masking was determined by each individual patient based on actual tests with wearable masking units. Variations in the individual characteristics listed above were not found to be significantly associated with the acceptance of masking and thus should not be used a priori to deny patients the opportunity for possible relief of their tinnitus. A masking indicator was found to be significantly (P = .03) associated with the acceptance of masking. This masking indicator is obtained by subtracting the loudness match of the tinnitus from the minimum masking level. When the masking indicator was 10 dB or less, the acceptance of masking was in excess of 50%. The data presented may help to dispel some current misconceptions about the masking of tinnitus.

Consumer Behavior↗