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L Pretel Serrano

Publications and source records attributed to L Pretel Serrano.

16 recordsLinked to original sources
PubMed2002

[Diagnostic utility of Osler's nodules in infectious endocarditis among parenteral drug users].

BACKGROUND: The objective of study is to describe of clinic, microbiological and histological data of five cases of infective endocarditis (IE) with Osler's nodes in intravenous drug users. PATIENTS Y METHODS: Prospectively, 43 cases of IE in intravenous drugs users was revised. In 4 patients, a aspirate puncture of Osler's node was performed and in one patient a biopsy of Osler's node was done with Gram's stain and culture of specimen. RESULTS: From 43 episodes of IE, 33 were right-side IE, 9 left-side y 1 right and left side. No patients with right-side IE presented Osler's nodes, however five of 10 (50%) patients with left-side endocarditis. In all of cases gram positive cocci were observed in Gram's strain and Staphylococcus aureus growth on culture of lesion with the same antibiotype than isolated from blood culture. One case a cutaneous biopsy was performed, and inflammatory infiltrate with necrosis was found. CONCLUSIONS: The Gram's strain and culture of specimen aspirated from Osler's nodes were of high utility in the diagnosis of IE in intravenous drugs users. The presence of Osler's nodes in a patient with infective endocarditis must be suggest that the location in left-side. These data suggest that Osler's nodes in infective endocarditis by S. aureus in intravenous drugs users was originated by microvascular septic emboli.

Adult↗
PubMed2000

[Infective endocarditis in intravenous drug users. Study of 34 cases].

OBJECTIVE: Infective endocarditis (IE) in injection drug users (IDU) have a special etiologic, epidemiological and clinical characteristics different to IE in the general population. The clinical and evolutive features of a group of IE in IVD are reported. METHODS: A retrospective analysis was made of 34 episodes (24 patients) of IE in IDU in the Catagena Area (Murcia, Sapin). RESULTS: A total 34 episodes, 18 was males (75%) and 6 (25%) females with a age media of 26.1 years (DE, 4.3). Eighty-four percents were infected with human immunodeficiency virus. The location of IE was right-side in 26 (73%), left-side in 7 cases (18%) and right-left in one (2%). Staphylocococcus aureus was isolated in 31 cases (91%), it was meticillin-resistant in 4 cases (13%); Pseudomonas aeruginosa, and Streptococcus equisimilis was isolated in one case each. Fever was present in 33 patients (97%) and more than half were cough, pleuritic chest pain and expectoration. Twenty-five patients with right IE has chest X-ray abnormal, specially nodules-infiltrates pulmonary. Vegetations were not observe in 7 (21%) occasions by transthoracic echocardiography. In six of 8 patients with left-side IE present a cerebri embolisms. Two patients with left IE death (21%). The rate of successful therapy in the right-side IE treated during 2 or 4 weeks were 100%. CONCLUSIONS: The IE in IDU is a entity produced mainly by S. aureus, affect preferentially a right-side cavities and the prognosis is generally good.

Adult↗
PubMed1993

[Diffuse pulmonary hemorrhage syndrome at a regional hospital. Description and clinical course].

The clinical characteristics and evolution of 15 patients with Diffuse Pulmonar Hemorrhage Syndrome are reviewed. According to etiology diseases are classified in three groups: 1) Basal Antimembrane Antibodies disease (66.6%), 2) Vasculitis-Granulomatosis (24.6%), and 3) Idiopathic (6.6%). Pulmonary Hemorrhage was the first manifestation of the primary disease in 80% of patients and was present in 100% of those patients with anemia and opacities in chest x-Ray and in 73% of those with renal insufficiency, nephritic sediment and respiratory insufficiency. To reach the etiological diagnosis, invasive techniques were needed in order to obtain samples for the pathology exam. Three patients died (20%) and 7 had a relapse (46.6%) during the first year. It is underlined the need of an empirical aggressive treatment with steroids and immune-suppress drugs before reaching the final etiological treatment.

Adolescent↗
PubMed1991

[An etiopathogenic and diagnostic update of vasculitis].

In this study, we examine with attention the latest etiopathogenic findings of this protein-like group of diseases in which even today, exist unclear and controversial aspects. We analyze from an immunological point of view either the role of immunocomplexes and the role of cell-mediated immunity, standing out the direct antibodies-mediated injury, especially emphasizing antineutrophil antibodies. Next, we describe steps and attitudes to be taken when facing one of these diseases diagnosis, including not only suspect, confirmation and degree of spreading, but also setting behaviour guidelines that make feasible the search of associate diseases and discarding other kind of diseases with which may arise some confusion.

Antibodies↗