PubMed Health⌕ Search

Biomedical subjects

L Proietti

Publications and source records attributed to L Proietti.

25 records · Page 2Linked to original sources

[In vitro exposure of U937 cells to potassium dichromate: study of apoptosis].

The aim of our study is to evaluate the genotoxic damage of cells treated with different concentrations of potassium dichromate. For this reason we have utilised U937 cells, a cellular line derived from acute promyelocytic leukaemia. Our results show that the minimum concentration of potassium dichromate induces apoptosis in the U937 cells and is of 600 microM, already after 12 hours, the cells treated with potassium dichromate with a concentration of 500 microM presented an apoptosis of 27% while the respective control showed a base apoptosis of 9.5%. Our experimental data indicate that the model adopted by us, may be a valid instrument to study the cytotoxic effects of compounds containing Chromium. In particular we have evidenced a clear genotoxic effect of these compounds demonstrated by a significant increase of the apoptosis percentage which is time and dose dependent.

Apoptosis↗

[Airbone contact dermatitis caused by latex exposure: a clinical case].

We describe the case of a nurse who showed eczematous lesions wide-spread over the neck and face. She worked as a attendant to a surgical chamber and wore vinyl gloves because of previous episodes of contact dermatitis caused by rubber gloves. The allergologic examination demonstrated that total IgE was 69.8 kU/1, both the Skin prick tests and the patch test for latex were positive. Persisting her dermatological symptomatology, in the suspicion of a airborne contact dermatitis, the nurse was removed and addressed to administrative functions for detecting the clinical follow-up. Fortunately, the eczematous manifestations spontaneously disappeared immediately after her transfer. In this case the presence of eczema mainly on air-exposed areas was interpreted as a sign of airborne contact dermatitis to latex. The case is reported in that the clinical picture is not very common.

Adult↗

[Smoking habits in health care workers: experience in two general hospitals of Eastern Sicily].

PURPOSE: The aim of our study was to assess the smoking habits in health care workers. MATERIALS AND METHODS: In concomitance with a medical examination for Health Care Surveillance requested by the Italian Laws (D. Lgs. 626/94), our operative units interviewed 2,000 persons (47.9% males, 52.1% females, mean age = 45 yrs (SD+/-9.41 yrs) working in two General Hospitals of Eastern Sicily. RESULTS: The prevalence of smokers was found to be higher in men (34.5%) than in women (33.6%), in Health Care Operators (36.4%) and professional nurses (36.2%) than in medical doctors (27.7%), in night-time workers (34,5%) then in day-time-workers (28,7%). The compliance with smoking restriction was found to be poor; in fact, 60% out of smokers declared to smoke during the working hours. CONCLUSIONS: This investigation has revealed the significant prevalence of tobacco smoking among the health care workers in general. We think that the inclusion of an anonymous questionnaire on smoking habits within the Services of Sanitary Surveillance may help in the national campaign against cigarette smoking.

Adult↗

[Airborne contact dermatitis].

A comprehensive bibliographical retrieval of case reports on "airborne contact dermatitis" (ACD) was performed. The present review deals with the first cases published in 1986, 1991, 2001 by Huygens as well as by Dooms-Goossens, and continues with the other pertaining clinical presentations until to day. Solid particles, rather than gases or droplets, are the most frequently reported causes of ACD.

Air Pollutants↗

[Unusual case of ano-rectal malformation].

The authors present an unusual case of anorectal malformation: it's an intermediate from with a cutaneous fistulous tract. This case is similar to that described in 1982 by the Japan study group of anorectal anomalies.

Anus, Imperforate↗

[Ingestion of caustics in childhood: proposal for a therapeutic protocol].

Caustic ingestion is a traumatic event not rare in the infancy. The authors, after a brief discussion of their cases and after a revision of the literature, propose a therapeutic protocol for the treatment of caustic ingestion in the infancy. This protocol is based on the esophagoscopy in the first day and on the antibiotic and corticotherapy in the first two weeks. When there is an esophageal stenosis, the authors propose weekly esophageal dilatations.

Anti-Bacterial Agents↗