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Biomedical subjects

L Q Xu

Publications and source records attributed to L Q Xu.

13 recordsLinked to original sources
PubMed2006

Superficial peroneal sensory and sural nerve conduction studies in peripheral neuropathy.

The objective of this study was to prospectively evaluate sensory nerve conduction studies (NCS) in the distal lower limbs in the electrodiagnosis of peripheral neuropathy. We prospectively studied 316 consecutive patients with surface stimulation and recording, in comparison with 90 control subjects. A total of 310 patients were found to have lower limb sensory NCS abnormalities. In these patients, the rate of detection of peripheral neuropathy with superficial peroneal NCS (88.5%) was significantly higher (P<0.001) compared with sural NCS (75%). The superficial peroneal NCS appeared to have a higher detection rate for peripheral neuropathy in our study, and its study can be adjunctive to sural NCS.

Adult↗
PubMed2005

Short-segment nerve conduction studies in the localization of ulnar neuropathy of the elbow: use of flexor carpi ulnaris recordings.

Short-segment nerve conduction studies were performed in 17 limbs with clinical features suggestive of ulnar neuropathy at the elbow. Recording from flexor carpi ulnaris yielded 93% sensitivity, compared with 71.4% when recording from abductor digiti minimi. The rationale underlying the technique is discussed. This approach should be of value as a diagnostic adjunct in technically challenging cases of ulnar neuropathy at the elbow.

Action Potentials↗
PubMed2004

Posterior antebrachial cutaneous nerve conduction study in radial neuropathy.

Radial neuropathy most commonly occurs as a result of external compression at the spiral groove region. The posterior antebrachial cutaneous nerve (PACN) conduction study was performed in 15 consecutive patients with radial palsy. Unilateral PACN abnormalities were present in 11 patients. A normal PACN study was correlated with clinical improvement at 3 months. Conversely, PACN abnormality was correlated with radial motor axon loss and a poorer prognosis. The PACN study is a simple adjunct which provides additional information relating to the diagnosis and prognosis of radial lesions.

Adolescent↗
PubMed2004

Posterior antebrachial cutaneous nerve conduction studies in normal subjects.

OBJECTIVE: The posterior antebrachial cutaneous (PABC) nerve is a sensory nerve that branches out from the radial nerve at the level of the spiral groove. Thus it can be affected in a radial nerve lesion at or proximal to its origin in the spiral groove. However, there has been limited knowledge about the normal values of PABC nerve conduction studies. This study was done to determine these normal values. METHODS: Sixty-three healthy adults (23 males) with a mean age of 41.5+/-10.6 (range, 20-90) years were recruited with informed consent. A total of 126 nerves were studied. The nerve conduction studies were performed using a Dantec Counterpoint EMG machine (Dantec, Skovlunde, Denmark). RESULTS: The mean+/-standard deviation values for the onset as well as peak latency, conduction velocity, amplitude and side-to-side amplitude ratio were 2.07+/-0.16 (range, 1.80-2.60) ms, 2.35+/-0.15 (range, 2.05-2.90) ms, 58.21+/-4.29 (range, 46.15-66.67) m/s, 6.10+/-2.11 (range, 2.90-13.00) microV and 0.83+/-0.12 (range, 0.60-0.99), respectively. There was a significant correlation between the subject age and the PABC onset and peak latencies as well as the amplitudes. CONCLUSIONS: The PABC nerve is assessable for nerve conduction studies and these normal values may be useful in evaluation of patients with suspected radial nerve lesions.

Adult↗
PubMed2001

[On cleanliness of hands in diminution of Ascaris lumbricoides infection in children].

OBJECTIVE: To study the relationship between cleanliness of children's hands and diminution of Ascaris lumbricoides infection. METHODS: Before the study all persons positive for ascaris eggs in the preliminary survey were treated with albendazole. Hand-washing habit before meal and after defecation was kept in children of experimental group, but not in the control group. Kato thick smear stool examination was done once every two months for one year to compare the new infection rates in children without ascaris infection in the two groups, and the reinfection rates in the cured negative cases were also compared between them in half a month after chemotherapy. RESULTS: All the new infection rates as well as reinfection rates of each reexamination in the experimental group were significantly lower than that of the control group (P < 0.001). Reexamination one year later showed that the ascaris infection rate of the experimental group was 35.2%, reducing by 48.5% as compared with 68.3% before the operation of the project; while ascaris infection rate of the control group was 73.7%, increasing by 78.0% as compared with 41.4% before the operation of the project. CONCLUSION: Washing hands with toilet soap to keep hands clean can significantly reduce ascaris infection rate.

Ascariasis↗
PubMed1995

Infantile hookworm disease in China. A review.

Hundreds of cases of infantile hookworm disease which shows bloody stools, melena, anorexia, listlessness and oedema, have been reported in China since the 1960s. Hookworm eggs were detected in due course in the faeces of the reported cases. With the exception of a single worm identified as Necator americanus, all the adult worms expelled following chemotherapy or examined at autopsy were Ancylostoma duodenale. Many children showed clinical manifestations and eggs in their faeces on day 1-26 after birth, and more cases occurred within 3 months of birth. Evidently, these infections were mostly transmitted from the mothers by transplacental and/or transmammary routes.

China↗
PubMed1995

Soil-transmitted helminthiases: nationwide survey in China.

A total of 2848 study sites, with about 500 people in each, were randomly sampled for this investigation which covered a total population of 1 477 742. By stool examinations using the Kato-Katz thick-smear and larval-culture techniques, overall prevalences of 47.0%, 18.8%, and 17.2% were obtained for Ascaris lumbricoides, Trichuris trichiura, and hookworm infections, respectively. The number of infections due to Ascaris, Trichuris, and hookworm was estimated as 531 million, 212 million, and 194 million, respectively. Egg counts showed that 75-95% of the subjects had light infections. Higher prevalences of ascariasis and trichuriasis were found in the age group of 5-9, 10-14 and 15-19 years, and among adults for hookworm. Students, farmers (including vegetable growers) and fishermen were the occupational groups with high infection rates. The prevalence of helminthiases was found to be closely associated with climatic and geographical factors. In view of the morbidity and mortality due to these helminthiases, their control, particularly in schoolchildren, is very important.

Adolescent↗
PubMed1994

Nationwide survey of human parasite in China.

A nationwide survey of human parasites in China was conducted during 1988-1992, with a coverage of 30 provinces/autonomous regions/municipalities (P/A/M). A total of 2,848 pilot sites in 726 counties were selected by random sampling, and 1,477,742 individuals residing on were surveyed by fecal examination. The status of paragonimiasis, hydatid diseases, cysticercosis and trichinellosis were summarized through data review. The overall infection rate of intestinal parasites was 62.6% whereas at provincial level, the highest infection rate (94.7%) was recovered in Hainan, and the lowest (17.5%) in Heilong-jiang. A high proportion (43.3%) of polyparasitism among the infected population (882,080) was revealed. Altogether 56 species of parasites comprising protozoa (19), trematode (16), cestodes (8), nematodes (12) and thorny-headed worm (1) were discovered. During the survey a new species and several new records were documented. The number of the population infected with common intestinal parasites was estimated. The diversities of parasite distribution were noted in different nationalities as well as in varied occupations.

Adolescent↗
PubMed1991

Selenium in Kashin-Beck disease areas.

In this article, the duplication portion technique was used to determine the daily intakes of selenium and ten other elements in the 24-h total diets collected in the typical Kashin-Beck endemic areas, i.e., Shanxi Province and Inner Mongolia Autonomous of China. The contents of Ca, Mg, Cu, Fe, Zn, Mn, Al, Sr, Ba, and P in freeze-dried samples were determined by ICP-AES. Se was determined by differential pulse catalytic polarography. The average Se contents in total diets of Shanxi Kashin-Beck endemic and nonendemic areas were 0.009 and 0.021 micrograms/g (dry weight), respectively (P less than 0.001), corresponding to the daily intakes for Se of 4.6 and 10.5 micrograms. After the Se-supplemented fertilizer was applied (225 g of Na2SeO3/ha), the average Se content in total diets of Kashin-Beck disease area was increased to 0.0336 micrograms/g, which corresponded to the average daily intake for Se of 16.8 micrograms. In Inner Mongolia Kashin-Beck endemic and nonendemic areas, the average Se contents in total diets were 0.006 and 0.017 micrograms/g, respectively (p less than 0.001), corresponding to the average daily intakes for Se of 3 and 8.5 micrograms. The contents of other ten elements in total diets in endemic and nonendemic areas were reported and compared.

China↗
PubMed1987

The effects of humic acid on the chemical and biological properties of selenium in the environment.

To shed light on the causes of Kaschin-Beck disease, which can be prevented by supplementation of the diet with sodium selenite, the interactions between inorganic selenium compounds (selenite and selenate) and humic/fulvic acid were investigated. Selenate was found to be slowly reduced to selenite by humic acid in acidic solution. Selenite was adsorbed on manganese dioxide and iron(III) oxide from solution to a much greater degree than on kaolin, humic acid, Yongshu soil, or silicon dioxide. Feeding mice a diet supplemented with sodium selenite increased the selenium concentration in the kidney, liver, spleen, lung, heart and blood. A diet containing sodium selenite and fulvic acid caused the selenium concentrations in the organs, with the exception of the spleen, to be lower than observed with the selenite-only diet. Selenium and fulvic acid increase the activity of glutathione peroxidase. Sodium selenite and fulvic acid injected in combination into the abdominal cavity of mice and rats were less toxic than either substance alone. Selenite and fulvic acid applied separately enhanced the luminosity of photobacterium phosphoreum T-3 at low concentrations but depressed the luminosity at higher concentrations. Selenite and fulvic acid in combination caused a larger enhancement and a smaller depression of the luminosity than observed with either substance alone. The hypothesis is formulated that Kaschin-Beck disease is caused by selenium levels insufficient to prevent the toxic effects of the organic compounds present in the drinking water of the regions in which the disease is endemic.

Animals↗
PubMed1987

Antagonism between selenium and humic acid.

In this work, two groups of experiments have been done by using mice and luminous bacteria. The results show that there exists an antagonism in toxicity between selenium and humic acid (HA) extracted from the drinking water in Kaschin Beck disease regions. In order to study the chemical mechanism of the antagonism, gel filtration and X-ray photoelectron spectroscopy techniques have been used to study the chemical bonding of the synthetic HA-Se in solution. The relationship between Se and HA in the cause of Kaschin Beck disease is discussed.

Animals↗