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Biomedical subjects

L Quinn

Publications and source records attributed to L Quinn.

28 records · Page 2Linked to original sources
PubMed1994

Clinical evaluation of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers.

OBJECTIVE: To evaluate the utility of a semipermeable polymeric membrane dressing for the treatment of chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS: Nineteen subjects with either insulin-dependent diabetes mellitus (IDDM) or non-insulin-dependent diabetes mellitus (NIDDM) and foot ulcers were randomly assigned to the polymeric dressing or conventional wet-to-dry saline dressings. Subjects had foot ulcer site measurements performed every 3 weeks. The subjects using conventional therapy were allowed to cross over to polymeric dressing after 2 months. RESULTS: At the end of 2 months, in the patients using the polymeric dressing, ulcer size was reduced to 35 +/- 16% of baseline. The patients on conventional therapy had an ulcer size of 105 +/- 28% of baseline (P < 0.03, polymeric vs. conventional). Patients initially treated with wet-to-dry saline were crossed over into the polymeric membrane treatment and demonstrated a decrease to 35 +/- 11% of baseline size (p < 0.02) after an additional 2 months. CONCLUSIONS: The semipermeable polymeric membrane dressing is a useful therapeutic option for treating uncomplicated chronic diabetic foot ulcers.

Chronic Disease↗
PubMed1991

Growth delay in homeless children.

This study compared the growth of homeless children with National Center for Health Statistics (NCHS) standards and with growth of age-matched domiciled children of similar income level. Homeless children (n = 167) had lower height percentiles when compared with domiciled children (n = 167; P less than .001) and when compared with NCHS standards (P less than .001). The weight-height percentiles of homeless children did not differ from NCHS standards; however, domiciled children had higher weight-heights when compared with the homeless (P less than .001) and with NCHS standards (P less than .001). After controlling via regression analysis for the effects of potentially confounding factors that affect growth, it was found that homeless children from larger families and with single mothers accounted for the lower height percentiles observed. After controlling for confounding factors, domiciled children still had increased weight-height percentiles when compared with the homeless group. Duration of homelessness was not associated with decreased height or weight-height among homeless children. Homeless children in this study exhibited a pattern of stunting without wasting which is characteristic of poor children experiencing moderate, chronic nutritional stress. They exhibited a greater degree of nutritional stress than domiciled children at a similar income level and than that reported in other groups of poor children in the United States. Preexisting social factors in the families of homeless children were important in explaining the observed growth abnormalities. Further exploration of the associations between social characteristics of homeless children and their families and the growth of these children is warranted.

Body Height↗
PubMed1989

Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis.

The prevalence of a recently described restriction fragment length polymorphism using Msp I for the serum amyloid P gene was determined in 5 groups of patients. Patients with reactive (secondary) amyloidosis, juvenile rheumatoid arthritis, related inflammatory conditions, or juvenile rheumatoid arthritis with reactive amyloidosis, and healthy control subjects were found to be polymorphic for 8.8-kb and 5.6-kb gene fragments; they either had one or the other or both fragments. No significant differences were seen between these groups with relation to this polymorphism, and no correlation with the presence of reactive amyloidosis was observed.

Amyloidosis↗
PubMed1983

A factor analytic study of screening scales of adjudicated delinquent males and females.

Obtained a factor analysis of demographic and behavioral variables from self-ratings and observations of trained raters on a sample of 200 incarcerated delinquents, which resulted in eight identifiable factors with eigenvalues over 1.0. These were described as: The undersized youthful offender with emotional problems, the aggressive threatening offender, the drug subculture repeat offender, the neurotic polyabuse offender, the institutionally unadjusted offender, the bright offender, the immature neurotic offender, and the "established" psychopathic offender. Results provide understanding of the relationships and disparities between self-ratings, the ratings of others, and demographic variables.

Adolescent↗
PubMed1981

Appearance of a sixth lactate dehydrogenase isoenzyme (LDH6) in a previously health patient.

We gave described a previously healthy patient with marked metabolic acidosis secondary to alcohol ingestion. An abnormal LDH isoenzyme (LDH6) located on the cathodic side of LDH5 after several episodes of shock was found in the patient's serum. We believe that the presence of LDH6 may occur as a result of shock from any cause and signifies a poor prognosis. The origin of LDH6 remains unknown.

Acidosis↗
PubMedDate not supplied

A pain management relief plan to improve patient care.

This article addresses a hospital's initiative to offer responsive pain management through the development of a pain management task force. It provides a sequential model and guide for nurse-managers to use in their own health care environments.

Humans↗