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Biomedical subjects

L Quiroz

Publications and source records attributed to L Quiroz.

15 recordsLinked to original sources

[Current status of esthetic dentistry].

In aesthetic odontology with adhesive materials, a close liaison between manufacturers and dentists is a much-needed prerequisite. Now more than in the past, when restorations were done on nobler materials, techniques and procedures involving composite materials must be performed with extreme precision, since such techniques are very sensitive.

Composite Resins↗

Intermittent continuous iv infusion of high-dose cyclophosphamide for remission induction in acute lymphocytic leukemia.

Cyclophosphamide was administered to 42 patients with acute lymphocytic leukemia (ALL) as a daily continuous iv infusion at a dose of 400 mg/m2/day x 5 days; the courses of treatment were repeated every 3 weeks. Of the 42 patients entered, 21 achieved a complete response, two achieved a partial response, 12 failed to respond, and seven were considered to have early deaths. The response rate was 69.5% if only patients who received adequate trials are considered; mean duration of response was 18.5 weeks and mean survival time was 24.2 weeks. Twenty-three patients had relapsed after previous chemotherapy, and 19 patients were untreated for advanced high-risk cases of ALL; no difference was found in the response rates, durations of response, and survival times between these groups. No significant genitourinary toxicity occurred. Myelosuppression became the dose-limiting toxic effect. Continuous infusion of cyclophosphamide is a clinically effective method of ALL treatment and may have a role in the initial combination regimens for this hematologic malignancy.

Adolescent↗