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Biomedical subjects

L R Lumpkin

Publications and source records attributed to L R Lumpkin.

14 recordsLinked to original sources

Neonatal lupus erythematosus. A report of three cases associated with anti-Ro/SSA antibodies.

Three patients had neonatal lupus erythematosus syndrome. All three infants were girls who presented with characteristic skin lesions but without evidence of congenital heart block. All three mothers were asymptomatic at the time of delivery and have remained so until the present time. All mothers were positive for anti-Ro/SSA antibodies, as were the infants prior to 6 months of age. Anti-La/SSB antibodies were not present in either the mothers or the infants. HLA typing revealed that two of the mothers were positive for B8 and DR3, while the third mother was positive for B8 and DR2. Two of the infants were positive for B8 and DR3, while the third infant was positive for DR2 only.

Antibodies↗

Subungual squamous cell carcinoma.

Subungual squamous cell carcinoma is a rare phenomenon. Diagnosis of this condition is often delayed because of a resemblance to a variety of benign inflammatory conditions. Metastases are unusual, but involvement of underlying bone is common. Curative treatment is achieved by amputation of the involved digit. The index of suspicion for malignancy in the face of an inflammatory nail condition unresponsive to standard treatment should be high, and a biopsy should be performed.

Aged↗

Renal cell carcinoma metastatic to skin.

A case of renal cell carcinoma metastatic to the skin is reported. Renal cell carcinoma is a relatively uncommon malignancy that frequently metastasizes to the skin.

Adenocarcinoma↗

Leprosy in five armadillo handlers.

Five patients with leprosy are presented. Each had had extensive and chronic contact with armadillos. No other potential risk factor for the development of leprosy could be identified. Since the nine-banded armadillo is a known carrier of leprosy in the southern area of the United States, we believe that these patients may have contracted leprosy from infected armadillos.

Adolescent↗

Therapy for acne vulgaris.

Although not curable or preventable, acne can benefit from adequate, appropriate therapy. Modern therapy for acne includes various topical agents highly effective against noninflammatory lesions, and oral or topical antibiotics effective against the inflammatory lesions. Long-term physical and psychologic scarring can be minimized by controlling acne in its active stages. Acne may flare during the first two to three weeks of intensive therapy. Unless undue side effects occur, any single agent or combination of agents should be tried for at least six weeks before being considered ineffective. Treatment needs to be individualized to achieve maximal effect.

Acne Vulgaris↗

Treating acne vulgaris.

While there is no single treatment plan that will work for every patient, acne can be controlled and long-term scarring can be minimized. Treatment must be individualized. Remember, there may be a "flare" when intensive therapy begins. Useful treatment methods include ultraviolet light, cleansers and soaps, peeling and drying agents, benzoyl peroxide preparations, abrasive soaps and scrubs, retinoic acid and oral antibiotics. The therapeutic choice depends upon the extent and severity of the disease.

Acne Vulgaris↗

Common skin cancers.

Explore the source record for details and available documents.

Basal Cell Carcinoma↗