PubMed HealthSearch

Biomedical subjects

L R Morris

Publications and source records attributed to L R Morris.

2 recordsLinked to original sources

Algorithms, hardware, and software for a digital signal processor microcomputer-based speech processor in a multielectrode cochlear implant system.

Software and hardware have been developed to create a powerful, inexpensive, compact digital signal processing system which in real-time extracts a low-bit rate linear predictive coding (LPC) speech system model. The model parameters derived include accurate spectral envelope, formant, pitch, and amplitude information. The system is based on the Texas Instruments TMS320 family, and the most compact realization requires only three chips (TMS320E17, A/D-D/A, op-amp), consuming a total of less than 0.5 W. The processor is part of programmable cochlear implant system under development by a multiuniversity Canadian team, but also has other applications in aids to the hearing handicapped.

Algorithms

Bicarbonate therapy in severe diabetic ketoacidosis.

Twenty-one adult patients with severe diabetic ketoacidosis entered a randomized prospective protocol in which variable doses of sodium bicarbonate, based on initial arterial pH (6.9 to 7.14), were administered to 10 patients (treatment group) and were withheld from 11 patients (control group). During treatment, there were no significant differences in the rate of decline of glucose or ketone levels or in the rate of increase in pH or bicarbonate levels in the blood or cerebrospinal fluid in either group. Similarly, there were no significant differences in the time required for the plasma glucose level to reach 250 mg/dL, blood pH to reach 7.3, or bicarbonate level to reach 15 meq/L. We conclude that in severe diabetic ketoacidosis (arterial pH 6.9 to 7.14), the administration of bicarbonate does not affect recovery outcome variables as compared with those in a control group.

Adult