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Biomedical subjects

L RUBIN

Publications and source records attributed to L RUBIN.

At least 19 recordsLinked to original sources

Fetal loss after cholecystectomy during pregnancy.

The histories of 17 patients who had a cholecystectomy during pregnancy were reviewed. All patients were operated upon for clinical recurrent biliary colic. Four patients aborted or had premature labour. It appears that there is an increased risk of fetal loss if cholecystectomy is performed during pregnancy. Because of this, it would appear reasonable to perform the operation only if the exigencies of the situation demand that surgery be done. It should be borne in mind that there may also be an increased fetal loss from recurrent biliary colic treated symptomatically, particularly if cholecystitis and jaundice were to complicate matters further. If operation is performed, the fetal loss rate will likely be in the neighbourhood of 15%.

Adult↗

Reduction of serum lipides and lipoproteins by ethionine feeding in the dog.

(i) The effects of daily oral administration of 125 mg of DL-ethionine upon the serum lipides and lipoproteins of dogs were studied. (ii) The feeding of the ethionine resulted in a prompt reduction in the levels of serum fatty acids, phospholipides, and cholesterol. See PDF for Figure At the end of 25 days, negligible amounts of these lipides remained in serum. (iii) A reduction in the levels of low- and high-density lipoproteins also resulted from the feeding of ethionine. In general, the extent of reduction in all lipoprotein fractions paralleled that observed in lipides. (iv) The removal of ethionine from the diet led to a prompt restoration of the concentrations of all lipide and lipoprotein constituents to normal.

Animals↗