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Biomedical subjects

L Rauramo

Publications and source records attributed to L Rauramo.

At least 55 records · Page 3Linked to original sources
PubMed1976

Effect of castration and long-term oral oestrogen therapy with oestriol succinate on serum lipids.

The effects of continuous oestriol succinate therapy (2 mg/day) of three years' duration on serum cholesterol, triglycerides and phospholipids were investigated on 50 women with a mean age of 48 years. In addition, the effects of castration only were investigated in 10 women with a similar mean age. One month after castration the serum cholesterol, triglyceride and phospholipid levels were significantly raised (p less than 0.05). During oestriol succinate therapy the cholesterol level tended to decrease. In the control group without hormone therapy, the cholesterol level showed a tendency to rise during the three years. The serum triglyceride and phospholipid levels remained almost unchanged during the oestriol succinate therapy and differed not from corresponding values of the control group.

Administration, Oral↗
PubMed1975

Oral conception and uterine size-ultrasonic study.

The effect of oral contraceptives on uterine size has been examined by B-mode ultrasonography. The subjects were 39 women (mean age 21) with regular menstrual cycles. None of them had taken the pill previously. The combined pill (E-con or Neo-Primovlar) was prescribed for 21 and the progestogen-only pill (Exluton) for 18 of the participants. The uterine size was measured with the help of B-scanning prior to the pill and after it was taken for three and six months. All three ultrasound examinations were carried out on the same day of the cycle plus or minus one day). No difference can be observed between the three measurements of uterine size either in the women on the combined pills or those on th progestogen-only pill (p greater than 0.05). The study will be continued. So far six women have been examined by ultrasound after having taken oral contraceptives for 12 months. Uterine size has remained unchanged in each case.

Adolescent↗
PubMed1975

The effect of systematic treatment of toxaemia of pregnancy upon fetal prognosis.

Systematic therapy for pre-eclampsia including diuretics was investigated in 604 patients in whom therapy was begun immediately the first symptoms appeared and continued until delivery. The control group consisted of 368 patients with toxemia from the two previous years who received no systematic therapy but who also underwent delivery at either the Turku City Maternity Hospital or the Women's Clinic of Turku University Central Hospital. Cases of pre-eclampsia gravis were significantly reduced (2.3 as compared with 7.3%). A significant difference was seen in the percentage of premature deliveries. In the experimental group this was 4.3% and in the control group 11.2%, (p less than 0.001). There was also a significant difference in the perinatal mortality, the values being 2.3 and 4.6%, respectively (p less than 0.05). The overal premature birth rate during these two periods remained unchanged, at 5.5 and 5.7%. The difference between the overall perinatal mortality rates was also slight (1.8 and 2.2%).

Acetazolamide↗