[Bacterial endocarditis in a case of substitution of the mitral valve with a Starr-Edwards prosthesis].
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Biomedical subjects
Publications and source records attributed to L Rebollar.
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Septal rupture (SR) during acute myocardial infarction (AMI) was found in 23 patients of 4 300 consecutive cases of AMI. In 55% the SR was diagnosed clinically by the appearance of a murmur, in 23% by shock and in 22% by heart failure. Eventually every patient developed a pan-systolic murmur. In 82% of the cases the murmur was best heard at the lower left sternal border. In half of the patients the location of the murmur suggested the possibility of papilary muscle rupture or dysfunction. In 68% of cases the rupture occurred during the first week after the onset of AMI. Cardiac catheterization was performed in 17 patients, pulmonary hypertension was found in all of them. Pulmonary blood flow was twice the systemic blood flow (P less than 0.005). Coronary angiograms performed in 6 patients showed three vessel disease in 5 cases. Five patients underwent surgery. Three of them survived. All of the 17 patients who had medical treatment died. Ten within the first week after AMI, 5 within the first month and 2 late deaths. Autopsy was performed in 15 cases. Eighty percent had coronary narrowing in several vessels. SR measured between 5 and 20 millimeters in 78% and was found in the anterior septum in 61%. In the cases who were in shock, the ventricular myocardium was extensively damaged. We conclude that once the diagnosis of SR is established, the patient should undergo surgical closure of the SR and coronary revascularization if necessary. Early surgical indication is particularly important in patients at risk of developing shock.
Between 1970 and 1979 one hundred and sixty seven patients underwent open mitral commissurotomy (OMC). In 22 of these cases the surgeon had to replace the mitral valve by a prosthesis. The authors discuss the pre-operative cardiac status, the surgical findings and mishaps which led to prosthetic implantation. Mean age for the group was 35 years; atrial fibrillation was found in 73%. Most patients were in class II and III of the NYHA, with a cardiac-thoracic ratio of 56-60%. On X-ray systemic emboli had occurred in 45% prior to surgery. All had predominant mitral stenosis without other valve lesions. Surgical findings were: valve fibrosis in 59%, sub-valvular fibrosis in 33%, moderate calcification in 27% and intracavitary thrombus in 12%. Half of the patients had associated mitral regurgitation (MR) of slight degree. In 11 patients, (50%), the surgeon aggravated the pre-existing MR while performing the valvotomy and had to replace the mitral valve (MVR). In 4 other patients, without previous MR a severe regurgitation was produced during valvotomy and MVR was required. In the 7 remaining, patients MVR was indicated because of valvular, subvalvular fibrosis or calcification. Surgical mortality was 14% as compared to less than 1% for OMC.
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