PubMed Health⌕ Search

Biomedical subjects

L Redvall

Publications and source records attributed to L Redvall.

6 recordsLinked to original sources

The safety and efficacy of MenoTreat, a new balloon device for thermal endometrial ablation.

BACKGROUND: An evaluation of the performance and safety of the prototype of a new device, MemoTreat (Atos Medical) for thermal endometrial balloon ablation in patients with menorrhagia. The evaluation was performed at four Swedish hospitals. METHODS: In total 51 consecutive, premenopausal patients, suffering from menorrhagia due to benign causes and not responding to conventional treatment, were treated between March 1997 and March 1998. The treatment entailed heated (85 degrees C) sterile saline circulated in a uterine balloon at a treatment pressure of 200 mmHg for 11 minutes. The procedure was performed mainly under general anesthesia and no pre-treatment endometrial thinning was performed. A validated pictorial assessment technique was used to evaluate changes in menstrual blood loss before and after treatment. Changes in quality of life and severity of dysmenorrhea were also evaluated. Data analysis was based on the 'intention to treat' method. RESULTS: The success rate in terms of a 50% reduction in menstrual bleeding was 84.3% at 6 months after treatment. Five patients became amenorrheic. The quality of life assessment showed substantial improvement and the severity of dysmenorrhea was markedly reduced. No intra-operative treatment complications occurred and the post-treatment morbidity was similar to that reported for other similar treatment methods. CONCLUSIONS: MenoTreat significantly reduced menstrual bleeding in menorrhagic patients, with a concomitant improvement in quality of life. The findings in this study resulted in a redesigned device with a thinner balloon catheter, improved cervical protection and treatment temperatures kept at a constant level.

Adult↗

A multicenter study comparing two endometrial sampling devices--Medscand Endorette and Pipelle de Cornier.

BACKGROUND: To compare two endometrial sampling devices Medscand Endorette and Pipelle de Cornier with respect to tissue collecting ability, diagnostic accuracy and side effects. METHODS: A prospective, multi-center, cross-over study in 152 women with a medical indication for endometrial biopsy. Samples were collected from each patient on the same occasion with both devices, the order of which was randomized. Statistical analysis was based on pairwise comparison in contingency tables with McNemars chi2 test. RESULTS: One hundred and forty-five of 152 (95%) women were successfully sampled. There was no difference between the devices concerning discomfort and bleeding. However, Medscand Endorette seemed to have a higher capacity than Pipelle for collecting an adequate sample. This difference was noted when the two devices were compared in the position as first instrument as well as when results were compared in the main target group for this type of examination, for women over 55 years. CONCLUSIONS: The new Medscand Endorette was preferred due to its higher capacity for collecting adequate samples.

Abdominal Pain↗

Menstrual status and menopausal age of middle-aged Swedish women. A population study of women in Göteborg 1968--69 and 1974--75.

A population study of women in Göteborg, Sweden, was carried out in 1968--69. Altogether 1 462 women participated (participation rate 90.1 per cent). Five age strata were studied: 38, 46, 50, 54 and 60 (women born in 1930, 1922, 1918, 1914 and 1908, respectively). The same women were re-studied in 1974--75. At this time 1 302 women participated, corresponding to 89.1 per cent of those studied in 1968--69 and 80.3 per cent of those initially sampled. The vast majority of the women had a natural menopause. The median age at the menopause was found to be about 50. The criteria for definition of menopause are discussed. No support was found for the theory of increased menopausal age with time. Estrogen therapy of postmenopausal women was found to be much more common in 1974--75 than in 1968--69.

Adult↗

Is the menopausal age rapidly changing?

A population study of women in Goteborg, Sweden was carried out in 1968--1969. Altogether 1462 women participated (participation rate 90.1%). Five age strata were studied: 38, 46, 50, 54 and 60 (women born in 1930, 1922, 1918, 1914 and 1908, respectively). The same women were re-studied in 1974--1975. Information about menopausal state and, in postmenopausal women, about menopausal age was obtained on both occasions. The information given by the women in 1974--1975 agreed well with the information given in 1968--1969. Very few women started to menstruate again, if the interval since the last menstruation had been 6 mth or longer. The vast majority of the women had a spontaneous menopause. The medians of menopausal age were found to be between 49 yr 7 mth (in women born in 1908) and 50 yr 5 mth (in women born in 1918). There was a tendency towards a continuously increased menopausal age with time as judged from women born in 1908, 1914 and 1918, respectively, but women born in 1922 were found to have a median menopausal age which was more similar to that of the women born in 1908 than that of the women born in 1918. Our sstudy has, thus, not supported the view that the menopausal age in rapidly changing.

Aged↗

The population study of women in Göteborg 1974--1975--the second phase of a longitudinal study. General design, purpose and sampling results.

A study of a population sample of women in Göteborg aged 38--60 years was carried out in 1968--1969. This population sample has been re-studied during the years 1974--1975. Altogether 1302 women participated in this second study, which means 89.1% of those studied in 1968--1969 and 80.3% of those initially sampled. Twenty-six women had died during the interval between the two studies, more than half of them from neoplastic disease. Information is given about those who had moved or were inaccessible at the time of the second study or who refused to participate. The performance of the examination is described and research projects are outlined.

Adult↗