Biomedical subjects

L Robinette

Publications and source records attributed to L Robinette.

5 recordsLinked to original sources

PubMed2001

Real-time I-MR-imaging--guided cryoablation of uterine fibroids.

In an ongoing prospective clinical trial, two patients with large, symptomatic uterine fibroids were treated with percutaneous magnetic resonance (MR)-imaging--guided cryoablation. Patients were followed with serial MR imaging studies and clinical evaluation according to Institutional Review Board protocol. Short-term imaging and clinical data were collected to assess the effects of the therapy. Both patients confirmed a significant reduction or elimination of their symptoms at 2 weeks after cryoablation. Measurements obtained from MR imaging performed after cryoablation documented a 65% and 53% reduction in each patient's fibroid volume at 8 weeks. Early clinical and imaging results confirm MR-imaging--guided cryoablation was effective at reducing or relieving these two patients' symptoms related to uterine fibroids and post-cryoablation imaging confirmed a significant reduction in fibroid volume.

Cryosurgery↗

PubMed2000

Calcium oxalate stones in feline littermates.

Two feline littermates were diagnosed with calcium oxalate uroliths. Both had been maintained on a commercially available dry diet with reduced magnesium and urine acidifying properties. One female littermate was diagnosed by visualising the stones by radiographs while the second littermate, also female, became blocked when one of the uroliths lodged in the urethra. Two other, unrelated cats in the household, of similar age and raised under the same conditions, did not develop calcium oxalate uroliths.

Animal Feed↗

PubMed1997

Better maternal outcomes are achieved with dexamethasone therapy for postpartum HELLP (hemolysis, elevated liver enzymes, and thrombocytopenia) syndrome.

OBJECTIVE: Our purpose was to determine whether the routine initiation of dexamethasone therapy in patients with postpartum HELLP (hemolysis, elevated liver enzymes, and thrombocytopenia) syndrome produces specific and general therapeutic benefits. STUDY DESIGN: In this retrospective, analytic study the puerperal courses of 43 women with postpartum HELLP syndrome who were treated with dexamethasone were compared with those of 237 similar patients who did not receive corticosteroids. Dexamethasone 10 mg intravenously at 12-hour intervals was given until disease remission was noted in treated patients, at which time up to two additional 5 mg intravenous doses were given at 12-hour intervals. RESULTS: The two patient groups were similar in regard to mode of delivery, gestational age, parity, and frequency of eclampsia. Compared with control subjects, dexamethasone-treated postpartum patients were more ill with significantly higher (p < 0.05) admission mean arterial blood pressure, higher serum uric acid level, and severe proteinuria. Dexamethasone administration was associated with a more rapid normalization of platelet counts and lactic dehydrogenase values. Most impressive was a clinically significant reduction of indicated transfusion and respiratory therapy, invasive hemodynamic monitoring, infectious or bleeding-related morbidity, and length of postpartum hospital course. CONCLUSIONS: Patients who received dexamethasone for postpartum-onset HELLP syndrome experienced a shorter disease course, faster recovery, less morbidity, and less need for other interventionist therapy compared with patients with HELLP syndrome who did not receive dexamethasone.

Adult↗

PubMed1978

Influence of the precedence effect on word identification by normally hearing and hearing-impaired subjects.

The influence of the precedence effect on word identification was investigated binaurally and monaurally with normally hearing and hearing-impaired subjects. The Modified Rhyme Test was processed through a PDP-12 computer to produce delay times of 0, 5, 10, 20, 40, 80, or 160 ms. The sounds were reproduced in a room by two loudspeakers positioned at +/-30 degrees azimuths in front of a subject at 50 dB SPL for normals and at the most comfortable level for impaireds. A babble of eight voices was added to reduce scores about 15% from the best values measured in quiet. Binaural and monaural word identification remained constant over a range of delays from 0 to 20 ms and declined for longer delays for both groups of subjects. The shapes of the word-identification curves were explained by self-masking (an overlap of consonants with their own repetitions) and masking (an overlap of consonants with preceding vowels or preceding and following words in sentence). Binaural responses for ten selected initial and final consonants showed various patterns of perception with delay. Some hearing impaireds showed more deterioration in word identification than others which might indicate that they experience more perceptual difficulties than normal listeners in places with reverberation or sound amplification.

Adult↗

PubMedDate not supplied

Reverberation as a parameter in clinical testing.

Word identification was measured binaurally and monaurally using the Modified Rhyme Test under noise and reverberation. Normally hearing and hearing-impaired subjects were tested. A change in reverberation time from 0.25 to 0.50 s in a small audiometric room caused a significant change in word identification scores in both groups of subjects. A simulated reverberation composed of five distinct reflections did not affect word identification. The binaural advantage (difference between the binaural and monaural scores) was significant for normally hearing subjects, while it was not significant for hearing-impaired subjects.

Acoustic Stimulation↗