Biomedical subjects

L Rockland

Publications and source records attributed to L Rockland.

3 recordsLinked to original sources

PubMed1990

Effects of trihexyphenidyl on plasma chlorpromazine in young schizophrenics.

This study investigated the effects of trihexyphenidyl on chlorpromazine (CPZ) plasma levels and clinical state in 20 relatively young schizophrenic patients diagnosed using the DSM-III. Spontaneous changes in CPZ plasma levels over time were also examined. Trihexyphenidyl significantly increased CPZ plasma levels (average 41%) but did not produce clinical change. The trihexphenidyl-induced increase in CPZ plasma levels was independent of CPZ oral dosage and of CPZ plasma levels. Chlorpromazine plasma levels decreased non significantly (about 13%) over the four weeks following steady state, but there was marked inter-subject variability, and CPZ levels rose in some subjects. Although identical CPZ doses produced widely variable plasma levels, CPZ plasma levels correlated significantly with oral dose. The views that antiparkinsonian drugs interfere with neuroleptic efficacy, and do so by lowering neuroleptic plasma levels, are questioned.

Adolescent↗

PubMed1985

Development of a scale for measuring techniques in the psychotherapy of borderline patients.

Studies of psychodynamic psychotherapy require an instrument to measure the application of the prescribed therapeutic techniques during ongoing treatment. The authors describe the development of such an instrument, the Therapist Verbal Intervention Inventory (TVII), designed specifically for use in the study of the treatment of patients with borderline personality disorders. The TVII was designed, in addition, to test the hypothesis that psychodynamic techniques defined at a middle level of inference could be reliably rated by trained clinicians. The authors present data on the inter-rater reliabilities and inter-rater agreements obtainable with the TVII in the hands of highly experienced clinicians and in the hands of an independent group of junior clinicians trained in its use. The TVII appears to be a potentially useful tool for monitoring psychotherapy techniques in ongoing studies of the treatment of patients with severe personality disorders. Psychiatrists at the advanced resident level or immediate postresidency level have been trained to use the TVII to rate videotaped therapy sessions reliably.

Borderline Personality Disorder↗

PubMed1975

Developing a psychiatric residency program: focus on the community.

A three-year general residency program intended to train psychiatrists to be as competent in group therapies and community work as in psychoanalytic psychotherapy was set up in a crisis center in the Bronx. Community members from the center's catchment area were actively involved in the planning for the training program and the center. The psychiatric residents in the program plan and revise their own curriculum, in collaboration with the faculty, and they work closely with faculty and staff in an apprentice system of learning. In this paper two faculty members describe the program's planning and the first year of operation; they also comment briefly on the program's current status. In the following paper two former residents present their view of the program's development and some of their experiences during the first year.

Community Mental Health Services↗