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L Rokitzki

Publications and source records attributed to L Rokitzki.

8 recordsLinked to original sources

[Prevention and therapy of obesity with diet and sports, an ambulatory therapy program for overweight children].

Dietary restriction together with ongoing power-orientated training provide best results in the therapy and prevention of obesity. Diet can reduce the resting metabolic rate by up to 20% within 14 days. Physical activity stimulates the resting metabolic rate and counteracts this energy saving effect, but is especially important for maintaining a steady state after weight reduction. Exercise reduces the risk factors accompanying obesity by favorable adaptation of the sympathoadrenergic system to physical activity. This can be seen in the effects on heart rate, stroke volume, blood pressure, as well as glycogenolytic and lipolytic activities. Body fat especially in the abdominal area, which is particularly connected with atherogenic risk, is diminished. Weight reduction is accompanied by a decrease of the cardioprotective cholesterol fraction. Diets high in unsaturated fatty acids combined with a staying power training have a synergistic effect: they reduce a decrease of HDL. It is difficult to demonstrate risk factors connected with overweight children. However, from the preventive medicine point of view it is advisable to start with therapeutic measures during childhood. In an out-patient pilot project we surveyed 18 obese children aged 9 to 13 years. The therapy plan consisted of dietary restriction (1200 kcal/d), an exercise program performed 3 times a week, and psychological assistance. All children of 12 to 13 years arrived at an overweight level less than 20%, the younger ones displayed a lower weight reduction effect. All 18 improved their aerobic capacity. In the 1st months of treatment, HDL-cholesterol decreased slightly, but increased above pre-treatment level, later on. We did not see any vitamin deficiencies during the therapeutic regimen.

Cardiovascular System

[Doping--also a problem in general practice?].

In 1986, the Medical Commission of the IOC defined doping as the use of pharmacological substances belonging to disallowed groups of active substances (stimulants, narcotics, anabolic steroids, beta-blockers, diuretics). With certain restrictions, this applies also to alcohol, local anesthetics and corticosteroids. The use of disallowed methods (blood doping, manipulation of a urine sample) is also forbidden. These days the greatest importance is attached to anabolic steroids (including testosterone), since these substances--discontinued in good time--cannot be detected on the day of competition but still have a promoting effect on performance. Competitive sports prepared the way here for the use of anabolic steroids in general athletics and in particular usually non-olympic sports (such as bodybuilding). Against this background, effects, adverse effects and the risks of anabolic steroid use are discussed. The aim must be to prevent the use of doping, especially in uncontrollable general sports, by promoting proper awareness.

Anabolic Agents

Blood and serum status of water- and fat-soluble vitamins in athletes and non-athletes.

Water- and fat-soluble vitamins have a key function in many metabolic processes and are of special importance for athletic performance. The water-soluble vitamins thiamine, riboflavin, and pyridoxine as well as the fat-soluble vitamins beta-carotene, retinol, and alpha-tocopherol were determined by methods based on high-pressure liquid chromatography (HPLC) in serum or blood of non-athletes and athletes of different sports such as bodybuilders, cyclists, cross-country skiers, marathon runners, and swimmers. The values for the water-soluble vitamin were much higher in athletes, whereas the values for the fat-soluble vitamins were not much different compared to those found in non-athletes.

Adult

[Selenium determination in blood plasma samples of high performance athletes].

Cooperating with the department "Sport- und Leistungsmedizin" of the university hospital of Freiburg/Brsg. we investigated the problem whether endurance stress leads to a significant change in the selenium blood concentration of athletes. We took blood samples of 13 test persons (11 men, 2 women) before, immediately after and 2 hours following a marathon course. The analyses of the concentration of selenium in plasma were performed by atomic absorption spectrometry AAS (molybdenum-coated graphite tube technique with L'vov platform as well as matrix modification with nickel nitrate in order to thermally stabilize the selenium). The selenium level of the plasma samples ranged between 41 and 153 micrograms/L. Our experiments have shown that running a marathon course does not lead to significant changes in the standard selenium plasma concentrations of the athletes.

Adult

[Serum and whole blood concentrations of fat and water soluble vitamins in normal persons and athletes].

Water-and fat-soluble vitamins have a key function in many metabolic processes and are of special importance for athletes. The water-soluble vitamins thiamine, riboflavin and pyridoxine and the fat-soluble vitamins beta-carotene, retinol and alpha-tocopherol were determined by High-Pressure-Liquid-Chromatography (HPLC). The mean serum values in non athletes (ng/ml) were for thiamine 9.23 +/- 3.62, riboflavin 6.17 +/- 2.46 and pyridoxine 12.41 +/- 4.59; the blood values for thiamine 20.12 +/- 7.58, riboflavin 13.43 +/- 3.97 and pyridoxine 18.75 +/- 6.66. The mean values of the fat-soluble vitamins were for beta-carotene 3.76 +/- 252 micrograms/l, retinol 598 +/- 141 micrograms/l and alpha-tocopherol 12.6 +/- 2.9 mg/l. The values of athletes (of different sport disciplines) for the water-soluble vitamins were much higher compared to the values found in non-athletes whereas the values for the fat-soluble vitamins were not much different.

Adult

[The effect of temazepam on the functional capacity and metabolic and cardiocirculatory parameters in consideration of the "jet lag" syndrome].

In a double-blind placebo controlled study, 14 male healthy volunteers were examined the morning after they had received an evening dose of 20 mg temazepam (Planum) with regard to functional capacity, cardial, cardiovascular and respiratory regulation as well as neuromuscular excitability and metabolic changes. After being exposed to the bicycle ergometer load, oxygen uptake, carbon dioxide output, glucose and lactate concentration were determined; furthermore the neuromuscular excitability of the musculus vastus medialis, musculus rectus femoris and musculus quadrizeps femoris was estimated. Despite unimportant capacity reductions (p greater than 0.05) concerning the maximum capacity (2.2%) as well as the maximum oxygen uptake (4.3%) under treatment with temazepam, there could not be proved any significant changes regarding cardiopulmonary and metabolic functions. On eastern and western flights, top athletes showed a very fast adaptation to the day-night rhythm without hang-over.

Adult

Influence of symptom-limited stress on blood lactate behaviour in coronary heart disease (CHD) patients.

In order to document the possible influence of stress limiting factors (STLF: chest pain, ST-segment depression) on exercise-induced blood lactate increase in CHD patients (post myocardial infarction) 88 males were examined in a stepwise bicycle stress test. Blood lactate samples were drawn at the end of each stress step. The patients were divided into 2 groups without (n = 45) and with (n = 43) STLF, higher blood lactate concentrations, however, were only observed in relation to the exercise intensity reached at the end of the stress test. Neither the symptom chest pain nor the degree of ST-depression showed a significant influence on the physical performance capacity and the lactate concentration at the anaerobic threshold. Nevertheless, a physical performance capacity above 1 W/kg seems to be necessary to reach the anaerobic threshold level. When the lactate measurement is used in CHD patients, the influence of age on the maximum lactate concentrations must be considered.

Aged

[Sports and diet--an ambulatory program for obese children].

In an out-patient programme, 18 obese children aged 9-13 years were attended to for 1 year. The project consisted of an exercise programme performed 3 times per week, dietary restriction to 1200 kcal/d and psychological approach. The aim, besides weight reduction and acquisition of a healthy individual nutrition habit, was to improve physical performance and to increase self-confidence. All children improved physical and coordinative capacity and staying power and showed considerably more self-confidence. Weight reduction to a level below 20% overweight was achieved in the group of 12-13 years of age, whereas younger children showed minor weight loss. In the early period of treatment, HDL-cholesterol generally decreased but increased within 4-5 months exceeding pretreatment levels. No vitamin deficiencies occurred.

Child