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Biomedical subjects

L S Agroskin

Publications and source records attributed to L S Agroskin.

At least 19 recordsLinked to original sources
PubMed1991

[Biometric studies in the cytological diagnosis of dysplasia and cancer of the uterine cervix].

Morphometric parameters were measured and specific light optic features of epitheliocyte nuclei examined in the cytologic preparations from 67 patients with various abnormalities of the cervix uteri multi-layer squamous epithelium by a present-day long-distance microimage analyzer. The most informative biometric parameters were detected, role of DNA cytophotometry defined, and algorithm of differential diagnosis between benign conditions, dysplasia, and carcinoma developed.

Female↗
PubMed1990

[Biometric research in the cytomorphological diagnosis of endometrial lesions].

Morphometrical and optical density (including DNA content) parametres of nuclei of the endometrial epithelial cells in smears of endometrial aspirates obtained from 57 women without endometrial disorders with hyperplastic, precancer conditions and endometrial cancer have been measured by using television image analyzer IBAS-2. Biometrical data have demonstrated a good correlation with cytomorphological diagnostic criteria and in 85.7% they have facilitated discrimination of the normal and hyperplastic epithelium from precancer and high differentiated endometrial cancer.

Adenocarcinoma↗
PubMed1989

[Biometric research in the diagnosis of precancerous states and endocervical cancer].

Smears of the endocervical channel taken from 58 patients with various endocervical conditions (reserve cell hyperplasia and dysplasia, reserve cell carcinoma in situ. Adenocarcinoma in situ, invasive glandular and poorly differentiated carcinoma) were stained by Feulgen method. Morphometrical (surface, perimeter, maximum and minimum diameter) and light microscopic (mean optical density of staining, its dispersion, DNA content) parameters of the epithelial cell nuclei were measured by means of telemetric image analyzer. The most informative biometrical indexes are found, the role of the DNA cytophotometry in the differential diagnosis is determined, the algorithm of the automated cytomorphological diagnosis of the dysplasia and endocervical carcinoma is developed.

Adenocarcinoma↗
PubMed1989

[Cytomorphologic and morphometric characteristics of the endocervical epithelium during malignant degeneration].

Cytohistological and biometric analysis identified certain cytomorphological features of reserve cell hyperplasia, dysplasia (atypical hyperplasia of reserve cells), reserve cell carcinoma in situ and adenocarcinoma in situ in the cervical canal. The role of TV analyser of microimages was established and their application to aid the practising cytologists in making diagnosis, particularly, in cases of conflicting cytologic and histologic evidence is discussed.

Adenocarcinoma↗
PubMed1988

[A trial of digital television cytophotometry].

A possible application of modern TV analyzers of microimages for absorption cytochemical investigation is considered. Photometric properties of the TV system are evaluated and methodical approaches to their improvement are given. Data on TV and scanning cytophotometry are compared when studying DNA contents in cells of different types.

Animals↗
PubMed1987

[A scanning cytophotometer for the analysis of closely contiguous objects].

A measuring complex including microscope-photometer and computer is described to be used for scanning of a sample inside of an arbitrary contour. The complex is supplied with a television channel for simultaneous control of the sample and photometric diaphragm, and also with a manual manipulator for setting the boundaries of the informational zone. At the end of scanning the cytophotometric and morphometric data are registered.

Computers↗
PubMed1978

Quantitative microspectral evaluation of the ratio of arginine-rich to lysine-rich histones in neurons and neuroglial cells.

Staining of nervous tissue sections with ammoniacal silver according to Black et al. has been confirmed to be a reliable histochemical colour reaction for quantitative evaluation of arginine-rich and lysine-rich histones in cell structures on the basis of determinations of the position of spectral curve maximum. Neurons of several brain nuclei which differed in predominating neurotransmitter did not differ in the ratio of arginine-rich to lysine-rich histones while some differences in this ratio were found out in the glial satelite cells adjacent to the corresponding neurons of these nuclei. Moderate circadian fluctuations were observed in the arginine-rich to lysine-rich histone ratio, these fluctuations being rather similar in the neurons studied and in the cells of perineuronal neuroglia.

Animals↗