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Biomedical subjects

L S Gonzalez

Publications and source records attributed to L S Gonzalez.

8 recordsLinked to original sources
PubMed2001

Medications in the breast-feeding mother.

Prescribing medications for a breast-feeding mother requires weighing the benefits of medication use for the mother against the risk of not breast-feeding the infant or the potential risk of exposing the infant to medications. A drug that is safe for use during pregnancy may not be safe for the nursing infant. The transfer of medications into breast milk depends on a concentration gradient that allows passive diffusion of nonionized, non-protein-bound drugs. The infant's medication exposure can be limited by prescribing medications to the breast-feeding mother that are poorly absorbed orally, by avoiding breast-feeding during times of peak maternal serum drug concentration and by prescribing topical therapy when possible. Mothers of premature or otherwise compromised infants may require altered dosing to avoid drug accumulation and toxicity in these infants. The most accurate and up-to-date sources of information, including Internet resources and telephone consultations, should be used.

Analgesics↗
PubMed2000

The middle school mentoring program in allied health: a proposed model.

This article describes the efforts of one group of participants in the Coalition for Allied Health Leadership program. Their purpose was to design a mentoring program for middle school students that will increase their awareness of the allied health professions as viable career options. A rationale for such a program and a program structure are provided as a beginning point for increasing awareness of allied health careers.

Adolescent↗
PubMed1998

Aminoglycosides: a practical review.

Aminoglycosides are potent bactericidal antibiotics that act by creating fissures in the outer membrane of the bacterial cell. They are particularly active against aerobic, gram-negative bacteria and act synergistically against certain gram-positive organisms. Gentamicin is the most commonly used aminoglycoside, but amikacin may be particularly effective against resistant organisms. Aminoglycosides are used in the treatment of severe infections of the abdomen and urinary tract, as well as bacteremia and endocarditis. They are also used for prophylaxis, especially against endocarditis. Resistance is rare but increasing in frequency. Avoiding prolonged use, volume depletion and concomitant administration of other potentially nephrotoxic agents decreases the risk of toxicity. Single daily dosing of aminoglycosides is possible because of their rapid concentration-dependent killing and post-antibiotic effect and has the potential for decreased toxicity. Single daily dosing of aminoglycosides appears to be safe, efficacious and cost effective. In certain clinical situations, such as patients with endocarditis or pediatric patients, traditional multiple dosing is still usually recommended.

Aminoglycosides↗
PubMedDate not supplied

Children's patterns of disclosures and recantations of sexual and ritualistic abuse allegations in psychotherapy.

Patterns of disclosures and recantations of abuse made in psychotherapy were examined in a sample of 63 children who reported sexual and ritualistic abuse in a preschool setting. Therapists completed a measure that instructed them to identify the time since the child began therapy when any disclosures or recantations were made, to specify the type of abuse disclosed or recanted, and to identify any events that might be related to the timing of a disclosure or recantation. The findings revealed that the majority of subjects (76.2%) disclosed abuse within the first month of therapy. Recantation occurred in 17 cases (27%) and all but two children who recanted redisclosed abuse after the initial recantation. There was some evidence that children's experiences within the legal system may have been associated with recantations. Subjects tended to make vague disclosures before revealing more specific acts, reveal less intrusive sexual abuse (e.g., kissing) before more intrusive types (e.g., intercourse), and to disclose ritualistic abuse after other types.

Adolescent↗