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Biomedical subjects

L S Gorman

Publications and source records attributed to L S Gorman.

2 recordsLinked to original sources
PubMedDate not supplied

Apoprotein assays: radial immunodiffusion versus an immunoturbidometric technique.

The measurement of apolipoprotein using radial immunodiffusion (RID) and Cobas-Bio immunoturbidometric assays is compared. Samples were obtained from 100 patients in a fiber-diet study. RID assays were performed using plates, standards, and diluent from Tago Inc. The immunonephelometric assays were performed on a Cobas-Bio with DENS program centrifugal analyzer. The correlation coefficient for the apolipoprotein Al was 0.90 and for apolipoprotein B was 0.91. The bias of the RID was to report higher values. The Cobas-Bio system affords the clinical laboratory with a reliable and cost-effective means for assessing these apolipoproteins.

Apolipoproteins↗
PubMedDate not supplied

Aging: laboratory testing and theories.

OBJECTIVE: To review theories of aging and the changes in laboratory test results that occur because of physical changes in the normal elderly patient. DATA SOURCES: Books on aging, laboratory test interpretation, and nutrition as well as published articles on aging, vitamins, and nutrition. STUDY SELECTION: Elderly people. DATA EXTRACTION: Survey of the literature. DATA SYNTHESIS: Aging theories may present possible aspects of the effects of aging on health in the elderly. Normal aging may lead to physical changes that alter laboratory test results without causing disease. Treatment of these "abnormal" results in the elderly may be detrimental to their health. CONCLUSION: As the elderly population increases, laboratorians will encounter an increasing number of elderly patients. Discriminating between truly abnormal test results and those caused by aging will require laboratory reevaluation of adult reference ranges.

Age Factors↗