Lead exposure and ALS.
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Amyotrophic Lateral Sclerosis↗
Biomedical subjects
L S Gresham
Publications and source records attributed to L S Gresham.
Amyotrophic lateral sclerosis and history of skeletal fracture: a case-control study.
A retrospective case-control study was conducted, using 66 amyotrophic lateral sclerosis (ALS) patients and 66 closely matched controls. Cases were ascertained primarily through a neurology clinic. A self-administered questionnaire probed for history of skeletal fractures. Using McNemar's test, no association was found between history of skeletal fracture and pathogenesis of ALS. No predilection for the head, neck, or spine was demonstrated. The extremities accounted for most fracture sites in cases and controls. Among cases, 68% of the fractures occurred before diagnosis, 58% occurring more than 10 years before diagnosis of ALS.
Amyotrophic Lateral Sclerosis↗
Amyotrophic lateral sclerosis and occupational heavy metal exposure: a case-control study.
A retrospective case-control study of occupational heavy metal exposure was conducted using 66 amyotrophic lateral sclerosis (ALS) patients and 66 age- and sex-matched controls. Cases were ascertained primarily through a neurology support and research clinic. The self-administered questionnaire probed potential exposure to nine heavy metals: aluminum, lead, lead alkyl, magnesium, manganese, mercury, mercury alkyl, nickel and selenium. Using McNemar's test and a Mantel Haenszel extended analysis, no association was found between heavy metal exposure and the pathogenesis of ALS in this patient population. Demographic factors, fracture history, immunizations, travel and other variables were similar in ALS patients and controls.
Adult↗
Breast cancer and mammography: summary of the educational impact of a low-cost mammography program.
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Adult↗