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Biomedical subjects

L S Lokshin

Publications and source records attributed to L S Lokshin.

14 recordsLinked to original sources

[First clinical test of the use of artificial blood circulation with auto-oxygenation].

Thirteen operations for ischemic heart disease were performed in the All-Union Surgery Centre of the AMS USSR using the method of simultaneous left and right heart bypass with oxygenation of the blood in the patient's lungs. This method was found to provide for a better gas exchange in artificial lung ventilation (ALV) with 30 per cent oxygen in the inhaled mixture, and for the reduction in the perfusion blood damage. The biventricular bypass is more complicated technically than the conventional artificial circulation (AC), but it is believed to be more physiological and cost-effective, which allows for considering it an alternative in aortocoronary bypass surgery.

Adult

[Experience in hemoconcentration by ultrafiltration in operations using artificial circulation at the All-Union Scientific Center of Surgery of the USSR Academy of Medical Sciences].

The article deals with the results of using ultrafiltration hemoconcentration in 649 operations conducted on the open heart with extracorporeal circulation at the All-Union Scientific Center of Surgery, USSR AMS during 1983-1989. The method allows control of hemodilution and colloid-osmotic pressure of plasma during the indicated interventions, lessens the loss of blood, and reduces the expenditure of donor blood.

Cardiac Surgical Procedures

Three clinical methods of circulatory assistance.

Three clinical methods of circulatory assistance are described: intraaortic balloon counterpulsation, left ventricular bypass using a roller pump, and the artificial ventricle. All three methods have hemodynamic effectiveness. The first method is indicated in cases of widespread cardiosclerosis and pronounced coronary insufficiency and may be contraindicated in pathology of the valvular apparatus. The second method demonstrated a temporary positive effect in patients in whom it was not possible to discontinue artificial circulation. The artificial ventricle is useful in treating patients with cardiogenic shock following cardiac surgery.

Assisted Circulation

[Treatment of acute cardiac insufficiency by left-ventricle bypass in cardiosurgical patients].

Severe cardiac insufficiency resistant to drug therapy developed in the immediate post-perfusion period in 1.5-2% of cardiosurgical patients who underwent operation in the recent 8 years. In view of this, such a method of mechanical sustenance of the weakened heart as left-ventricular bypass (LVB) was suggested. LVB lasting 5.7 hours on average, was carried out in 56 patients in the immediate postperfusion period in adequately corrected heart valvular disease. It was shown that by unloading the left ventricle by means of a roller pump the average arterial pressure can be raised, the average left-ventricular pressure lowered, and the dose of the administered cardiotonics reduced. All this contributes to the restoration of the patient's own adequate circulation. Owing to LVB, cardiac activity was restored in 56% of patients, 41% of patients recovered and were discharged from the hospital. The results bear evidence that LVB is an effective method for sustenance of circulation in cardiosurgical patients.

Acute Disease