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Biomedical subjects

L S Manvelov

Publications and source records attributed to L S Manvelov.

At least 19 recordsLinked to original sources

[Physical activity and physical work capacity of patients with initial manifestations of cerebrovascular disorders in arterial hypertension].

The routine protocol of general and neurological examinations and some special questionnaires were used to examine physical activity (FA) and physical working capacity (FWC) in a random population from one of the Moscow districts which included 1200 persons (males and females aged 30-64 years). The majority of the examinees were those who had slight and moderate exercises, mainly sitting work, did few or no physical exercises. The proportion of persons with low physical activity increased with age both among males and females. The ratios generally remained despite the presence of early signs of abnormal blood supply. Bicycle ergometer testings showed a significant reduction in the physical working capacity of the patients with abnormal brain blood supply, in a greater extent, in arterial hypertension. Decreased functional activity and functional working capacity may regarded as one of the risk factors for cerebrovascular disorders, in arterial hypertension in particular, and should be borne in mind in implementing preventive measures.

Adult

[Neurological aspects of medical ecology].

The paper deals with a number of problems facing clinical neurology. They arise in neurological disorders stemming from unfavourable ecological conditions.

Air Pollutants, Occupational

[Characteristics of cerebral hemodynamics and the resistance to major cardiovascular diseases based on the data of an epidemiologic survey].

In the cross-sectional population study of 411 subjects aged 35-64 years and longitudinal 5.5-year follow-up of 157 aged 20-54 years, a relationship was examined between pulse blood flow to the cerebral vessels, their tone as assessed by rheoencephalography and resistance to arterial hypertension, coronary heart disease, and brain vascular lesions. The proportion of healthy persons (without the above-mentioned diseases) was shown to be larger if the pulse blood flow to the cerebral vessels was higher and their tone was lower. In the longitudinal study, the probability to remain healthy was demonstrated to be increased with elevated pulse flow to the cerebral vessels.

Adult

[Effectiveness of a stroke prevention program in a high-risk group].

As a result of screening of males born in 1922-1931 (n = 2435) a group with a high risk for stroke development (n = 620) was identified. A total of 430 of these patients were followed up for 2 years. At the final stage the authors collected data on 80% of the patients who had undergone the primary examination and carried out a new screening of age-matched males. The morbidity rate related to cerebral stroke was 2.59% in the high risk group and 1.48% in the remaining population. The incidence of myocardial infarction in the above two groups was 5.01% and 1.80% respectively. At the same time 55.9% of new cases of cerebral stroke and 44.2% of myocardial infarction occurred in individuals who were not included into the high risk group and had an "intermediate" risk of the development of these diseases. It is concluded that the problem of combating cerebral stroke cannot be solved by putting emphasis exclusively on prevention in high risk groups and that it should be combined with wide-scale prophylactic work among the population.

Cerebrovascular Circulation