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Biomedical subjects

L S Matthews

Publications and source records attributed to L S Matthews.

At least 19 recordsLinked to original sources

Scapulothoracic anatomy for the arthroscopist.

Because endoscopic management has recently been introduced as treatment for painful subscapular snapping, we designed a cadaveric study to identify the boundaries of the scapulothoracic spaces and the relationship of important neurovascular structures to safe portal sites for arthroscopic surgery. We studied eight fresh, unembalmed cadaveric shoulders by anatomic dissection alone and eight fresh, unembalmed cadaveric shoulders by dissection after arthroscopy. We noted the following findings: (1) the scapulothoracic articulation has two triangular spaces, the serratus anterior space and the subscapularis space, that are divided obliquely by the serratus anterior muscle; (2) the boundaries of the larger serratus anterior space include the chest wall anteriorly, the serratus anterior muscle posteriorly, and the rhomboids medially; (3) the boundaries of the subscapularis space are the serratus anterior muscle anteriorly, the subscapularis muscle posteriorly, and the axilla laterally; and (4) a well-defined bursa occupies the serratus anterior space. Based on these findings, we recommend that portals for arthroscopic surgery should be inferior to the spine of the scapula and three to four finger-breadths from the vertebral border of the scapula (1) to avoid the neurovascular structures at the superomedial angle of the scapula, (2) to avoid the dorsosacpular nerve and artery, and (3) to prevent perpendicular orientation of the arthroscope to the lateral chest wall.

Arthroscopy

Use of patellar allograft to reconstruct a patellar tendon-deficient knee after total joint arthroplasty.

A catastrophic complication after total knee arthroplasty (TKA) is rupture of the patellar tendon. Several techniques for treatment have been described, including cast immobilization with or without operative repair, the use of a semitendinosus, fascia lata, or hamstring tendon autogenous graft, the use of a Dacron 4-mm vascular graft (U.S. Catheter and Instrument, Glen Falls, NY), the use of bovine xenograft and even transplantation of an entire allograft extensor mechanism. Treatment results of patellar tendon rupture after TKA can be discouraging. Altered tissue quality secondary to connective tissue diseases, diabetes, rheumatoid arthritis, lupus erythematosus, secondary hyperparathyroidism, or concurrent steroid medications contributes to poor results. Additionally, no one treatment has provided consistent clinical success. Successful treatment of a patient with a ruptured patellar tendon after TKA using the bone-patellar tendon-bone allograft commonly used for anterior cruciate ligament reconstruction is reported.

Aged

Displacements of the menisci under joint load: an in vitro study in human knees.

The purpose of this study was to test whether the menisci displace under joint compression combined with internal-external torques and anterior-posterior forces at fixed flexion angles. We further determined differences in displacements between the medial and lateral menisci. Loads were applied to the joint, and joint load and displacements were measured. Meniscal displacements were measured radiographically. With a joint compressive load of 1 kN, internal and external joint rotations caused the lateral meniscus to displace, on average, 0.37 mm deg-1 in the anterior-posterior direction, while the medial meniscus displaced 0.19 mm deg-1. Anterior and posterior joint translation, performed under 1 kN joint compression, caused the lateral meniscus to displace, on average, 0.66 mm mm-1 in the anterior-posterior direction, while the medial meniscus displaced 0.43 mm mm-1. Greater meniscal displacements were found at 15 and 30 degrees flexion than at 0 degrees for the lateral meniscus in internal rotation. Lateral meniscal displacements were larger than those of the medial with posterior tibial translation at full extension and with internal rotation.

Femur

Localized pigmented villonodular synovitis of the patellar fat pad: a report of two cases.

Pigmented villonodular synovitis (PVNS) of the knee is a well-recognized entity. We report on two cases of localized PVNS that involved the patellar fat pad, an area of involvement not previously reported. Diagnostic and therapeutic arthroscopies were performed, and typical findings of localized PVNS were found. Complete resection of the lesions were performed arthroscopically. At short-term follow-up, all symptoms had resolved. Arthroscopy can be used as an effective diagnostic tool for identification of intraarticular PVNS of the knee. In the case of localized involvement, it also can be considered as definitive treatment.

Adipose Tissue

Arthroscopic treatment of synovial diseases of the shoulder.

A wide spectrum of synovial disorders may affect the shoulder joint. This article provides a detailed description of the clinical features of synovial disorders of the shoulder. The role of arthroscopic surgery in the diagnosis and treatment of this spectrum of disease is discussed also.

Arthritis

Diverse effects of insulin-like growth factor I on glucose, lipid, and amino acid metabolism.

The metabolic effects of recombinant human insulin-like growth factor I (rhIGF-I) on glucose, amino acid, and free fatty acid (FFA) metabolism were examined in nine healthy nonobese subjects. Each received a 3-h primed continuous infusion of rhIGF-I (20 micrograms/kg bolus, 0.4 microgram.kg-1.min-1) while maintaining euglycemia using an exogenous glucose infusion. Total IGF-I levels increased from 125 +/- 11 to 444 +/- 22 ng/ml, and free IGF-I levels rose from undetectable to 73 +/- 5 ng/ml. Insulin levels fell from 95 +/- 9 to 64 +/- 8 pM, and C-peptide fell from 453 +/- 48 to 206 +/- 29 pM; circulating glucagon levels also declined from 72 +/- 9 to 42 +/- 4 pg/ml, rhIGF-I produced a two- to threefold increase in glucose uptake as measured by [3H] glucose (from 10.3 +/- 0.6 to 27.4 +/- 3 mumol.kg-1.m-1), and, despite the fall in insulin secretion, there was a marked 60-70% inhibition of hepatic glucose production. Furthermore, FFA and branched-chain amino acids declined by 40-60% (411 +/- 58 to 165 +/- 36 and 406 +/- 23 to 219 +/- 14 microM, respectively). Our data demonstrate that rhIGF-I has potent effects on glucose (hepatic and peripheral), lipid, and amino acid metabolism in normal humans. The scope of the actions of rhIGF-I closely resemble those of insulin, despite a concomitant inhibitory effect on insulin secretion.

Adult

Proximal femoral bone density and its correlation to fracture load and hip-screw penetration load.

The bone mineral density of 22 random, fresh proximal human femora was estimated by roentgenography using the Singh index (SI) and measured using a regional bone mineral density computed tomographic protocol. Uniaxial compression was used to produce an impacted subcapital fracture. The femoral heads then were isolated and mounted on a sliding screw plate compression device and loaded to failure in a push-out or hip-screw penetration mode. Wide intraobserver variation, poor reproducibility, and poor prediction of the experimental fracture properties of the proximal femur were noted for SI values. Regional bone mineral density provided a reliable estimate of both the gross fracture loads and hip-screw penetration loads. In addition, there was a high correlation between trabecular density and the experimental fracture properties of the proximal femur. Therefore, The validity of the SI as an indicator of the mechanical properties of the proximal femur should be reconsidered.

Biomechanical Phenomena

Interlocking intramedullary nails. An improved method of screw placement combining image intensification and laser light.

Insertion of distal interlocking screws in femoral nails can be technically demanding and may entail substantial exposure. A method of insertion of femoral interlocking screws that uses a laser guiding system in addition to the standard image intensifier was used in an attempt to improve the accuracy of distal screw placement and to limit radiation exposure. Using this technique, 97% of the distal femoral drill holes attempted were successfully made with the first pass of a drill. Little or no resistance to the drill was met from contacting the femoral nail. Average fluoroscopy time was 0.4 minute. Laser-assisted screw placement requires relatively inexpensive modifications of existing equipment and is easy to master. Compared with the more commonly used freehand method, laser-assisted screw placement appears to offer a reduction in the amount of time and radiation exposure required to insert distal interlocking femoral screws.

Bone Nails

The prosthesis-bone interface in total knee arthroplasty.

Classic methods of implant component fixation, including the use of screw and impact-tapered, interference-fit stabilization, have provided longevity of function for total knee arthroplasties (TKAs). Optimal cement stabilization may be limited by the degradation characteristics of methyl-methacrylate. Modern application of porous coating for bony ingrowth fixation has not been as successful as expected, particularly as applied to the tibial component in TKA. Based on their in vivo research, the authors have developed a tibial component with an array of porous-coated cones that ensure immediate fixation and a graduated stress field to the host trabecular bone. This may improve the reliability and durability of tibial component fixation.

Animals

Airport detection of modern orthopedic implant metals.

The sensitivity of airport metal detectors to a variety of orthopedic implants shows that total hip and total knee replacements, intramedullary nails, hip compression screws, and bone plates can escape detection. The metallurgic composition of the undetected implants were titanium, titanium-aluminum-vanadium alloy, cobalt-chrome-molybdenum alloy, and some stainless steel. The implants were tested individually, in combination, and as a whole in each of three different metal detectors. Only one of the screened implants activated a metal detector: an old Austin Moore straight fenestrated endoprosthesis that individually activated one of the three metal detectors. All of the other screened implants were not detected by any of the three tested metal detectors. Furthermore, the Moore endoprosthesis failed to activate two of the three tested metal detectors. Metal objects are identified by metal detectors based on their ferrous content. Contemporary orthopedic implants use little, if any, ferrous metal and therefore escape detection by airport metal detectors.

Aviation

Trabecular bone remodeling: an experimental model.

An experimental model, capable of inducing controlled stress fields to the distal femoral metaphyses of large dogs, is presented. This model utilized an implantable hydraulic device incorporating five loading cylinders and platens in direct contact with an exposed plane of trabecular bone. A microprocessor controls the loading characteristics, and finite element models were created to calculate the induced stress and strain fields. The trabecular remodeling response is measured using serial in vivo computed tomography, in vitro microcomputed tomography, and histologic analysis. The results of the experiment indicate that significant remodeling can be induced by the activated implant. An increase in trabecular orientation toward the loaded platens was observed, and a statistically significant decrease in connectivity was documented. The greatest effect was associated with a change in the loading rate. A fast rise time (70 ms) loading waveform induced significant bone ingrowth at the implant interface when compared to a slow rise time waveform (700 ms), and demonstrated high correlations with the calculated stress fields as remodeling approached an equilibrium state.

Animals

The joint-contact area of the ankle. The contribution of the posterior malleolus.

Eight ankles from fresh cadavera were tested under simulated clinical conditions to determine the effect of increasing the size of the posterior malleolar fracture on the contact area of the ankle joint and on the distribution of joint pressure. The surface area of contact decreased with increased size of the posterior malleolar fragment. However, the documented changes were smaller than expected on the basis of the findings of Ramsey and Hamilton; they reported a 42 per cent reduction in contact area with only a one-millimeter lateral shift of the talus, which clinically would be associated with a similar one-millimeter shift of the distal tibial fragment. In addition, clinical experience has shown a high rate of post-traumatic degenerative arthritis associated with an inadequately reduced one-half-size posterior fragment. There were considerable changes in the load-distribution patterns, with increased confluence and concentration of loads as the size of the fragment was increased. In plantar flexion, many specimens had three separate areas of contact between the tibia and the talus. With increased size of the posterior fragment, the three areas of contact always joined to become one. Similarly, for all positions of the ankle, increased size of the posterior fragment caused decreases in the contact area. The maximum loss of contact area was 35 per cent for specimens with one-half-size fractures that were tested in the neutral position.

Ankle Joint

Arthrodesis of the knee with an intramedullary nail.

The cases of twenty patients who had an arthrodesis in which an intramedullary nail was used for stabilization were reviewed at an average follow-up of six years. The predominant indications were infection after total knee arthroplasty and post-traumatic pain and instability. Other indications included aseptic loosening of the components of a total knee arthroplasty, reconstruction after resection of a giant-cell tumor, non-union of a fracture of the distal part of the femur or the proximal part of the tibia, and failed external-compression arthrodesis. Success was achieved in seventeen patients (85 per cent), and functional stability immediately postoperatively was gained in all twenty. Of the three patients in whom the arthrodesis failed, all had sustained an intraoperative fracture, and infection eventually developed. Of the twelve nails that were secured to the greater trochanter with a loop of stainless-steel wire, none showed evidence of proximal migration. Of the eight nails that were not thus secured, two migrated proximally, necessitating removal of the nail. Two drawbacks to this operation are the long duration and the large amount of blood that is lost. The major advantage is that a high percentage of patients have progression to a stable fusion despite serious problems. Furthermore, all but seven patients (including the six who had a tumor or who had sustained an intraoperative fracture) were able to bear full weight by the second postoperative week. Only a few patients needed an external support for walking.

Adult

Traction force profiles associated with the use of a fracture table: a preliminary report.

A load cell was developed that can reliably monitor longitudinal traction forces applied to limbs during several different orthopaedic procedures. This permitted determination of tensile loads and the effects of patient limb positions on tension magnitudes. The relationships between the magnitude and duration of applied tension to functional nerve changes were also studied. This preliminary report reviews traction force data on seven patients for eight operations. Mean peak loads for femoral, tibial, and hip procedures were 686, 356, and 306 N, respectively. Adduction of the limb around a fixed peroneal post caused great increases in traction forces.

Adult

Treatment of juxtaarticular nonunion fractures at the knee with long-stem total knee arthroplasty.

A retrospective study of ten patients with juxtaarticular nonunions at the knee treated with long stem total knee arthroplasty was performed. The average age of the patients was 76 years old, with an average follow-up of 36 months. The nonunions were present for an average of 36 months. There were six patients in the series with prior total knee arthroplasty. Clinical union was achieved in all ten patients. All patients improved their ambulatory status. Range of motion improved from an average preoperative range of 40 degrees to an average postoperative range of 85 degrees. Complications occurred in three of ten patients, with one being a postoperative infection. Surgical techniques are described to aid in treatment of difficult juxtaarticular nonunion fragments.

Aged

Results of treatment of displaced patellar fractures by partial patellectomy.

The results of partial patellectomy as a treatment for displaced patellar fractures were assessed retrospectively with use of clinical, radiographic, and isokinetic strength-testing criteria. Forty patients who had been followed for an average of 8.4 years were studied. In the extremity that had been operated on, the mean active range of motion was 94 per cent, the circumference of the thigh was 100 per cent, and the strength of the quadriceps was 85 per cent of these measurements in the contralateral extremity. The over-all result was rated as excellent in twenty patients, good in eleven, fair in six, and poor in three. There was a significant statistical correlation between the type of fracture and the outcome. The results of this study indicate that partial patellectomy can be an effective treatment for selected patellar fractures.

Adult

Tips of the trade #28. Accurate tunnel placement using drill guides in knee ligament reconstruction.

Knee ligament reconstruction is optimized when intra-articular grafts are placed isometrically. Several drill guides have been designed to facilitate accurate tunnel placement. The use of an intra-articular keying hole, made with a burr, enhances proper and secure drill guide placement. Sterile mineral oil lubrication of the drill guide components will help prevent their distortion and will eliminate improper tunnel placement.

Anterior Cruciate Ligament