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Biomedical subjects

L S Matveeva

Publications and source records attributed to L S Matveeva.

At least 19 recordsLinked to original sources
PubMed1986

[Functional reserves of myocardial perfusion in patients with chronic ischemic heart disease with varying degrees of damage of the coronary arteries].

A comparative study of data provided by coronaro-angiography and myocardial perfusion scintigraphy (resting and exercise tests), and clinical/electrocardiographic results of the exercise test in 102 chronic coronary patients demonstrated that non-invasive myocardial perfusion 201Tl scintigraphy combined with threshold bicycle-ergometric exercise adds considerably to the clinico-electrocardiographic assessment of the exercise test and thus helps to detect myocardial blood supply (perfusion) disorders in some of coronary patients with doubtful or negative test results. Reduced functional reserves of myocardial blood supply, as reflected in deficient perfusion at the peak of threshold exercise, are seen in all coronary patients with angiographically intact coronary arteries and in most patients with both the so-called "functionally-insignificant" and marked coronary arterial stenosis (94.7 and 88.3%, respectively).

Adult↗
PubMed1986

Diagnostic value of pulsed Doppler echocardiography in combined heart defects.

26 patients with combined heart defects were examined by means of ultrasound methods (one-dimensional, two-dimensional and Doppler echocardiography). The results were compared with the results of clinical and roentgenological examinations. Taking into account literary data on high sensitivity and specificity of Doppler echocardiography, its informative value was assessed in cases when affection of two or more valves results in a balancing of haemodynamic changes. It was documented that pulsed Doppler EchoCG makes possible to assess the character and the direction of blood flow in different phases of the cardiac cycle in the heart cavities and the great vessels, and thereby provides additional information on the involvement of the valvular apparatus and on the state of haemodynamics. The sensitivity of this method is particularly high in the detection of regurgitant flow.

Adult↗
PubMed1985

[Interrelation of the state of perfusion and the coronary vascular bed in patients with chronic ischemic heart disease].

Coronary angiographic and scintigraphic (using 201Tl) studies in 139 patients with verified diagnosis of chronic coronary heart disease demonstrated high sensitivity (85.6%) of myocardial perfusion scintigraphy with respect to detecting disorders of myocardial blood supply due to the stenosis of major coronary arteries and microcirculation disorders. False negative scintigraphic results in the screening for perfusion defects are commonly due to the shortcomings of semiquantitative assessment of the scintigrams.

Adult↗
PubMed1985

[Intravenous isoproterenol administration for diagnosing ischemic heart disease in women: a comparison with the data from bicycle ergometry and selective coronary angiography].

The significance of the test with intravenous injection of isoproterenol in the diagnosis of coronary heart disease (CHD) was evaluated in comparison with the clinical, bicycle ergometry and selective coronarography data obtained in 65 women. Twenty-four patients presented with stenosing coronary atherosclerosis and 41 patients had normal coronary arteries. On the use of the electrocardiographic signs of myocardial ischemia the sensitivity of the isoproterenol test in the diagnosis of hemodynamically appreciable coronary atherosclerosis was 74%, the specificity 78%. The sensitivity and specificity of bicycle ergometry were 66 and 90%, respectively.

Adult↗
PubMed1984

[Roentgenologic evaluation of myocardial contractility in heart valve diseases].

The authors compare the roentgenological findings with the parameters of contractility obtained during heart catheterization in 49 patients with mitral valvular disease and aortal valvular disease. The parameters are shown to be correlated with regard to the nature of valvular damage, characteristics of the impairment of the intracardiac hemodynamics and myocardial contractile function. Certain tendencies of this dependence are tabulated.

Adolescent↗
PubMed1984

[The dipyridamole test in the diagnosis of ischemic heart disease in women].

Bicycle ergometry and the dipyridamol test were performed in 25 females with coronary artery stenosis and 42 with unchanged coronary arteries (according to the coronarography data). The sensitivity of the dipyridamol test was 80% at its specificity was 78% according to the electrocardiographic data that correlated well with those of bicycle ergometry. The dipyridamol test can be used for examining females with suspected coronary heart disease.

Adult↗
PubMed1984

[The bicycle ergometry test in the diagnosis of ischemic heart disease in women (a comparison with selective coronary angiographic data)].

The bicycle ergometric test and selective coronary angiography were performed in 105 women with 39 of them presenting stenosis of the coronary arteries. Judging by the electrocardiographic criteria, the test sensitivity was 68%, its specificity being 90%. Normalization of the ECG at the height of the submaximal exercise in the presence of the baseline changes in the ST-T interval may serve as an additional criterion of the absence of coronary artery stenosis. When the test was evaluated by clinical and electrocardiographic criteria, its specificity decreased.

Adolescent↗
PubMed1983

[Prostaglandins in the renal vascular bed in arterial hypertension of different etiologies].

Levels of PGE2, PGF2 alpha and renin activity were measured in renal venous blood of 29 patients with essential hypertension (EH), 23 patients with renovascular hypertension (RVH) and 10 patients with unilateral pyelonephritis and high arterial hypertension. The pattern of change in renal venous PG content was found to be related to the type of renal lesion: the level of PGE2 was lowered and PGF2 alpha/PGF2 ratio increased in the blood outflow from the kidneys of EH patients and from ischemized kidneys of RVH patients as compared to similar parameters in the outflow from contralateral kidneys of patients with RVH and pyelonephritis. Venous levels of both PGs were the highest in pyelonephritis-affected kidneys. Renal venous PG levels go down in all cases as the disease grows older. An acute drop in arterial pressure is accompanied with increased withdrawal of PGF2 alpha from the kidneys and enhanced renin activity in renal veins, while PGE2 drops simultaneously. PGF2 and PGE2 showing different trends of change in response to falling arterial pressure suggests increased transition of PGE2 to PGF2 alpha under the effect of enhanced PG-9-ketodehydrogenase activity. In the abdominal aorta, the scope of drop in arterial pressure correlates to the change in PGF2 alpha level, that is an evidence of PG direct involvement in the autoregulation of renal blood flow.

Dinoprost↗
PubMed1983

[Idiopathic hypertrophic subaortic stenosis: functional condition of the left ventricle, central and pulmonary hemodynamics (an angiocardiographic study)].

Two-projectional left ventriculography, with pressure recording in the aorta, left ventricle, right chambers of the heart and the pulmonary artery, was performed in 26 patients with idiopathic hypertrophic subaortal stenosis free of intraventricular pressure gradient. Considerable left-ventricular hypertrophy associated with this condition was shown to be of "low-stress" origin and strictly concentric in nature, left ventricular systolic function keeping within normal range, and diastolic function being disordered as manifested in significantly increased filling pressure and disordered left ventricular relaxation. Disordered geometry and local contractility of the left ventricle reflected in hypercontraction of the outlet orifice, papillar muscles and posterior wall, combined with its reduced longitudinal contractility results in excessive tension of tendinous chordas and abnormal movement of the anterior mitral cusp towards the hypertrophic ventricular septum and marked mitral regurgitation.

Adolescent↗
PubMed1983

[Mechanisms of regulation of high cardiac output in patients with hypertension (angiocardiographic study)].

To identify mechanism conditioning high cardiac output, an angiocardiographic study was conducted in 39 patients with essential hypertension. Increased stroke and cardiac output was found to be due to increased venous inflow, with inotropic condition of the hypertrophic myocardium being reduced in spite of enhanced general pumping function of the left ventricle. As arterial hypertension tended to stabilize and cardiac output declined, total peripheral resistance assumed the principal responsibility for its regulation, whereas at earlier stages of the disease it shows either normal, or even reduced levels, and venous inflow is the principal factor controlling cardiac and stroke output.

Adult↗