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Biomedical subjects

L S Rubin

Publications and source records attributed to L S Rubin.

18 recordsLinked to original sources
PubMed1994

The integration of voice science, voice pathology, medicine, public speaking, acting, and singing.

The integration of voice science, voice pathology, medicine, public speaking, acting, and singing has been central to evolution in all fields. The Voice Foundation Symposia have played a seminal and central role in fostering integration among disciplines. The result has been an improvement in the knowledge and practice in each field. And the future promises to be even more informative and exciting.

Congresses as Topic↗
PubMed1980

Pupillometric studies of alcoholism.

Several parameters of the pupillary light and dark reflexes were employed as indices of sympathetic-parasympathetic activity in comparing alcoholics to nonalcoholics at rest, during stress, and following the termination of stress. Moreover, as the alcoholics were given the choice of drinking at frequent fixed intervals, the control values of autonomic activity were correlated with the subsequent decision to drink or not to drink. Overall differences in autonomic reactivity between nonalcoholics and alcoholics were found and drinkers were differentiable from alcoholic abstainers on several parameters.

Adult↗
PubMed1976

Amplitude of pupillary contraction as a function of intensity of illumination in schizophrenia.

When the amplitude of pupillary contraction of normal, healthy adults was binocularly recorded as a function of increasing intensity of light-stimulation, a linear relationship was found between the amplitude and log intensity. Schizophrenic patients deviated significantly from this systematic response pattern in two ways. One group of patients (35%) manifested the same pupillomotor threshold as the normals, however, as the intensity of light was systematically increased mean amplitude and rate of pupillary contraction fell below that evidenced by normals. Another group of patients (65%) were distinguished by an abnormal pupillomotor threshold, specifically requiring an increase of one log intensity unit for the elicitation of a recordable pupillary contraction. Moreover, as the light intensity increased, the mean amplitude of contraction was significantly attenuated at all intensities below that of the normals and of the schizophrenics who manifested a normal pupillomotor threshold. In addition, it was found that the average diameter of the dark-adapted pupil was smaller in both groups of patients as compared to the healthy adults, although there was no difference between the patient groups on the variable. As pupillary reactivity to stress in normals is characterized by an increase in the diameter of the dark-adapted pupil representing increased sympathetic outflow and by a reciprocal increase in the diameter of the light-adapted pupil representing increased supranuclear inhibition, the results of the study do not support the assertion that schizophrenics are hyperaroused. It is suggested schizophrenia may be considered a tonic autonomic dysfunctional state of mock-arousal characterized by either abnormally high levels of central supranuclear inhibition or by defective sympathetic outflow, or both.

Adult↗