Biomedical subjects

L S Slobodianikova

Publications and source records attributed to L S Slobodianikova.

2 recordsLinked to original sources

PubMedDate not supplied

[Stabilization of proteases from Bacillus subtilis in solution].

Experiments were carried out to study the effect of the styrene and maleinic acid copolymer on the activity of proteases produced by Bacillus subtilis--protosubtilin G15x. Unlike the hydrophilic ethylene--maleinic acid copolymer, styrenated maleinic acid produced a stabilizing effect on proteases via hydrophobic interaction. It is suggested that at least two forms of the enzyme differing in their activity and stability are involved in the process of inactivation. On the basis of the data obtained a scheme of protease inactivation is proposed.

Bacillus subtilis↗

PubMedDate not supplied

[Immobilization of Bacillus subtilis proteases on a styrol copolymer with maleic anhydride with covalent and coordination bonds].

Insoluble enzymes have been obtained through an interaction of the complex preparation of proteases, protosubtilin G15x, with the sterol and maleic anhydride copolymer in aprotic dipolar solvents and as a result of formation of mixed enzyme-polymer complexes of protosubtilin G15x and the sterol and malic acid copolymer in aqueous solution in the presence of metal ions. The effect of metal ions on the yield and activity of the resultant immobilized preparation has been studied.

Bacillus subtilis↗