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L S Taylor

Publications and source records attributed to L S Taylor.

53 records · Page 3Linked to original sources
PubMed1982

Optimal dietary conditions for hemoccult testing.

Preliminary rehydration of Hemoccult II slides increases slide sensitivity for blood and lowers the false-negative rate for colorectal cancer. To test the effect of this modification on the false-positive rate due to peroxidase-containing foods, 156 healthy young subjects crossed between diets of differing peroxidase content. Hemoccult II slides were prepared in duplicate for testing with and without rehydration. When developed without rehydration, only seven (0.4%) of 1856 slides were positive, the positive results occurring with challenge diets containing 250 g rare red meat. With preliminary rehydration, 53 (5.7%) of 926 slides were positive, in 26 (17%) of the 156 subjects on a challenge diet that included rare red meat and uncooked fruit and vegetables. Well-cooked red meat also gave positive tests, Diets excluding red meat but with large quantities of uncooked fruit and vegetables produced only five positive results in 314 rehydrated tests, in 3 of 53 subjects. On a strict low-peroxidase diet, two of 310 tests, in 2 of 52 subjects, were positive. Rehydration of Hemoccult slides and exclusion of red meat and certain other high-peroxidase foods should give optimal sensitivity and specificity for colorectal cancer detection. The effect of these conditions on yield of lesions and false-positive rates should be tested in screening programs.

Adult↗
PubMed1981

The mechanisms of athermal microwave biological effects.

A brief survey of current ideas about the physical mechanisms of low-level millimeter/microwave-biological effects is given, and the experimental evidence supporting these ideas is reviewed. The conjectural models do not yet represent a complete physical theory, but they do counter the idea that low-level effects are physically impossible and suggest experiments.

Animals↗
PubMedDate not supplied

Hypertension management: a comparison of urban versus rural general practitioners in Western Australia.

1. We have conducted a survey of 75 rural and 75 urban randomly selected general practioners (GPs) in Western Australia to ascertain how closely current practice mirrors published Australian guidelines for the management of hypertension. 2. Fifty-one rural and 49 urban GPs completed the 19 item questionnaire. The two groups were well matched in terms of age and years in general practice. An assessment of the criteria utilized to diagnose hypertension revealed a tendency for much greater scatter in the cut points used to define systolic compared to diastolic hypertension, but no systematic difference between urban and rural GPs. 3. After an initial finding of mild hypertension the follow-up time to the next check-up was significantly longer for rural patients compared to urban patients (72 +/- 13 and 36 +/- 5 days respectively, P < 0.01). Urban GPs reviewed established hypertensive patients more commonly at 1-3 monthly intervals (89%) while rural GPs reviewed more commonly at 3-6 monthly intervals (86%). 4. In terms of target blood pressure (BP) for BP reduction, 67% rural compared to 83% urban GPs aimed for a systolic BP of < 140 mmHg (P = 0.06), while 95% of both groups aimed for diastolic BP < 90 mmHg. 5. The profile of first line antihypertensive agents most commonly used was also similar in both groups with 46% preferring angiotensin converting enzyme inhibitors, 18.5% diuretics, 18.5% beta blockers, 16% calcium entry blockers and 1% prazosin. 6. This study demonstrates a clear preference for the newer anti-hypertensive agents.(ABSTRACT TRUNCATED AT 250 WORDS)

Antihypertensive Agents↗