Endolaryngeal CO2 laser microsurgery of early vocal cord cancer. A retrospective study.
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Carbon Dioxide↗
Biomedical subjects
L Sávay
Publications and source records attributed to L Sávay.
[Primary CO2 laser chordectomy in vocal cord carcinoma].
A study was performed with laryngo-microscopic CO2 laser surgery on 55 patients suffering from histologically verified glottic cancer. They were treated by either "superficial laser chordectomy", or "partial cordectomy", "total chordectomy", or "extended chordectomy" in stages Tis = 7, T1a = 34, T1b = 11, and T2 = 3. All patients with Tis remained free of tumours, in stage T1a 88% (30/34) of the patients after laser chordectomy and 2 patients after partial- and total laryngectomy. In stage T1b the recurrence rate was higher (3/11 = 27%), but 2 patients after partial laryngectomy, and one patient after radiotherapy have become tumour-free, and thus all patients in this group are free from tumours. One of the 3 patients in stage T2 developed a local tumour recurrence, but after partial laryngectomy he is free from tumour and hence all 3 patients are still alive. Laser chordectomy proved a sufficient therapeutic procedure in 47 (85%) of 55 patients; eventually 95% of the patients became tumour-free. The authors emphasise that CO2 laser chordectomy is a modern and useful surgical method in the therapy of a vocal cord carcinoma, provided adequate follow-up and the possibility of "salvage" surgery are available.
Adult↗
Adenocarcinoma of ceruminous glands. Ultrastructural, immunohistochemical and lectin histochemical studies.
A case of ceruminous adenocarcinoma is reported. The tumor destroyed the right pyramid, widely invaded the base of the skull and caused death shortly after the diagnosis. Distant metastases were not found by autopsy. The tumour cells reacted with epithelial markers and with the antibody against S-100 protein. Heparan sulphate proteoglycan seemed to be a good marker for detecting basement membrane ruptures and concomitant tumour invasion. Among the lectins BS-I and PNA gave the strongest reactions in the stroma. This is the first immunohistochemical and lectin histochemical report on ceruminous adenocarcinoma.
Adenocarcinoma↗
[A case of ceruminous adenocarcinoma. Ultrastructural and immunohistochemical studies].
Case of ceruminal adenocarcinoma is reported. Tumor was diagnosed in advance stage, and within a month following diagnosis it caused death. Tumor started from right auditory canal, undermined the pyramidal bone and infiltrated great part of right side of base of skull, narrowing great foramen to a certain extent. Metastasizes were only the right of dura. Besides electron microscopic studies, authors performed the immune-histochemical and lectin-histochemical examination of tumor the first time.
Adenocarcinoma↗
Reconstruction of spinal accessory nerve after radical neck dissection.
Resection of the spinal accessory nerve in cases of radical neck dissection often causes considerable damage to the function of the shoulder girdle; it leads to limitation of the motion of the upper limb and pain in the shoulder girdle. It seems a sensible compromise to reconstruct the spinal accessory nerve in one-stage operation with radical neck dissection, which can often prevent extensive atrophy of the trapezius muscle, with a resultant improvement in the chance of successful rehabilitation. The technique of the operation is described: after completion of radical neck dissection, in one-stage operation an autogenous nerve transplant from the n. auricularis magnus is sewn onto the central and peripheral stumps of the spinal accessory nerve, which are protected by a "vein-muff" and the fascia of the muscle. After such spinal accessory nerve reconstruction, subjective complaints and objective symptoms were much milder in 6 patients than in the control group, which consisted of 10 patients who underwent a similar operation but without spinal accessory nerve reconstruction.
Accessory Nerve↗
Laser lingual tonsillotomy.
The classic surgical procedures for treatment of complaints caused by hyperplasia and chronic inflammation of the lingual tonsil are difficult, and may involve serious complications. Eleven patients with hyperplasia of the lingual tonsil were treated with a Tungsram TLS 61 CO2 laser coupled to an operating microscope. The average duration of hospitalization was 3-4 days. The advantages of the use of a CO2 laser are haemostasis, sealing of the nerve endings, decrease of postoperative pain, and no postoperative oedema, which is important because of the closeness of the larynx. There were no serious complications either during surgery or in the postoperative period, and the complaints of all 11 patients were eliminated or reduced.
Adult↗