Chest pressure discomfort & pain.
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Adult↗
Biomedical subjects
L Santo
Publications and source records attributed to L Santo.
Multichannel photometer-nephelometer.
We describe an instrument for monitoring either transmitted or scattered light intensity, or both, simultaneously on up to eight channels. The use of a laser light source (at 632.8-nm wavelength) provides high accuracy and dynamic range: optical density can be measured from 0.0004 up to 6, and a scattered light fraction down to 10(-6) can be resolved. Built-in thermostat and magnetic stirrers allow precise monitoring of aqueous microbial growth over a practical range of 4 orders of magnitude of cell concentration.
Escherichia coli↗
Metabiolic products of microorganisms. Tirandamycin B(author's transl).
Streptomyces flaveolus, strain Tü 1240 produces besides Tirandamycin A, a hitherto unknown antibiotic, which is closely related to Tirandamycin A. The new antibiotic Tirandamycin B contains one additional hydroxylgroup. Both antibiotics exhibit a similar antimicrobial spectrum and they seem to have the same mechanism of action. According to the data obtained from mass spectrometry, 13C-and 1H-NMR spectra formula II could be deduced for Tirandamycin B.
Aminoglycosides↗
Ultrastructural studies of sporulation in a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis.
Morphological studies of a conditionally temperature-sensitive ribonucleic acid polymerase mutant of Bacillus subtilis have revealed that sporulation is inhibited at stage II when the cells are grown at 47.5 C. Growth and sporulation occur normally at 30 C with the mutant. The mutant grows normally at 47.5 C but is prevented from sporulating at the nonpermissive temperature by an abnormal septation during forespore membrane formation which prevents the subsequent engulfment process (stage III). The mutation affects the normal functioning of ribonucleic acid polymerase at the nonpermissive temperature resulting in abortive sporulation.
Bacillus subtilis↗
Ultrastructural analysis of sporulation in a conditional serine protease mutant of Bacillus subtilis.
The morphological characteristics of wild-type Bacillus subtilis and a temperature-sensitive serine protease derivative have been observed during vegetative and sporulation time periods. At 30 C wild-type and mutant cells grow and sporulate identically. At 47.5 C wild-type and mutant cells grow identically, but the mutant cells are blocked at stage 0 or I in the sporulation sequence. Wild-type cells sporulate normally at 47.5 C.
Bacillus subtilis↗
Ultrasonic calling in rodents: a new experimental approach in behavioural toxicology.
Ultrasonic calls are emitted by many species of rodents in a variety of situations. In particular, infants commonly emit such calls when removed from the nest; the rate and intensity of calling are related to the degree of development of homoiothermy. The relevant biological significance of these signals is documented by their capability to promote parental behaviour, such as maternal retrieval. There is recent evidence that ultrasonic vocalization in rodent pups could be valuable as a bioassay in Behavioural Toxicology. In particular, the results of our recent studies together with those of other authors suggest that ultrasonic calls emitted by infant rats could be considered a useful test in detecting subtle effects of adverse treatment during development.
Animals↗
A non-thermal effect of millimeter wave radiation on the puffing of giant chromosomes.
A non-thermal influence of millimeter wave radiation (swept in frequency from 64.1 GHz to 69.1 GHz, sweeptime 6 s, and with stabilized frequencies of 67.200 +/- 0.001 GHz and 68.200 +/- 0.001 GHz, power density less than or equal to 6 mW/cm2) on the puffing of giant chromosomes of the midge Acricotopus lucidus (Diptera, Chironomidae) was found. The effect is manifested as a reduction in size of a specific puff that expresses genes for a secretory protein. The non-thermal nature of the effect was proved by experiments in which the sham-exposed sample was warmed up by 2.5 degrees C which is more than the eight-fold microwave induced temperature increase of less than or equal to 0.3 degrees C. Concerning the very low photon energy of mm-waves compared to the thermal energy kT, it seems likely that the coherence of the radiation is essential for the observed effect.
Animals↗
[A case of Sweet's syndrome with rheumatic onset].
Sweet's syndrome (acute febrile neutrophilic dermatosis) is a disease characterized by the abrupt onset of red, tender, cutaneous plaques on the face, extremities and upper trunk accompanied by fever, arthralgia or arthritis and neutrophilic leukocytosis. Histologically, there are distinctive, dense, dermal infiltrates of neutrophils. This case report describes a case of Sweet's syndrome characterized by rheumatic onset, microhematuria and subcutaneous nodular lesions on the legs resembling erythema nodosum. The etiopathogenesis and relationship between Sweet's syndrome and infectious and non infectious diseases is discussed. The overlap between this peculiar syndrome and some aspects of inflammatory rheumatic diseases, namely seronegative spondyloarthritides, is suggested.
Adult↗