PubMed Health⌕ Search

Biomedical subjects

L Schrire

Publications and source records attributed to L Schrire.

8 recordsLinked to original sources
PubMed1987

The prevalence of human isolates of Salmonella subspecies II in southern Africa.

The Salmonella Reference Centre in Johannesburg received 14059 strains of human origin between 1979 and 1984. A significant proportion (6.3%) proved to belong to subspecies II. The majority were cultured from faecal material, usually associated with symptoms related to the gastrointestinal tract. They comprised 884 isolates, represented by 203 serotypes, of which 45 were new serotypes. The poor hygienic conditions found in many rural areas, together with possible contamination of food and water by wild animals, may contribute to the greater frequency of human S.II infections and the widespread occurrence of unusual serotypes in man in this geographic region.

Adult↗
PubMed1984

A laboratory assessment of the activities of four aminoglycosides.

An in vitro comparison of the activities of gentamicin, tobramycin, amikacin and netilmicin against selected clinical isolates showed differences in the susceptibility of individual strains to the four drugs, as well as substantial differences in sensitivity patterns between genera. Sensitive strains of Klebsiella and Enterobacter were most susceptible to netilmicin, but amikacin was more active against resistant strains. Tobramycin was most active against sensitive strains of Pseudomonas aeruginosa, but resistant strains were more susceptible to amikacin. In serious infections caused by these Gram-negative bacilli knowledge of the organism's identity and susceptibility may help in the selection of the most suitable aminoglycoside.

Amikacin↗
PubMed1982

Activities of four aminoglycosides at subbactericidal concentrations.

This report describes an activity range index derived from the minimal bactericidal and antibiotic concentrations of four aminoglycosides against four representatives of clinically important gram-negative bacilli. The ranking orders of in vitro activity differed from those using the minimal bactericidal concentration or the minimal antibiotic concentration as the sole criterion.

Aminoglycosides↗