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Biomedical subjects

L Sebai

Publications and source records attributed to L Sebai.

14 recordsLinked to original sources
PubMed1999

[Role of lactate dehydrogenase (LDH) level in the aqueous humor in the diagnosis of retinoblastoma (RB)].

In spite of the progress of the imagery in ophthalmology, the retinoblastoma remains in some particular cases, difficult to make. Moreover, the therapy sanction is often heavy. The lactate dehydrogenase (LDH) dosage in aqueous humor is an invasive technique conceivable when there are diagnosis problems particularly in retino-blastoma of old children and in affections simulating retino-blastoma. The purpose of this work is to lay out three observations where the LDH dosage enabled to keep the retinoblastoma diagnosis in one 8-year old child and eliminate it in two children having pseudoglioma with spontaneous evolution allowing to confirm the non-tumoral nature of the affection. Thus, the technique of LDH dosage has been reliable for the 3 cases which we have introduced. The authors compare the reliability of the different cytochemical techniques during the retinoblastoma diagnosis.

Aqueous Humor↗
PubMed1998

[Penetrating keratoplasty in primary congenital glaucoma].

PURPOSE: We present preliminary research on penetrating keratoplasty in corneal dystrophy secondary to congenital glaucoma. The aim was to analyse the functional and anatomic results of this morbid condition where visual prognosis is usually poor. PATIENTS AND METHODS: Six cases of congenital glaucoma in which the ocular pressure is controlled were studied. Age varied from 10 months to 11 years, the medium age was 47.7 months (SD: 42.8). These patients underwent penetrating keratoplasty. Recession varied from 3 months to 29 months, with a medium recession of 18.4 months (SD: 11.54). RESULTS: Anatomic results: the graft remained transparent in 5 eyes. Some postoperative complications were noticed: ocular hypertonia medically treated in one case, minor uveitis in one case, total cataract operated by phacophagy with a final outcome of ophthalmomalacia, buphtalmia (31.5 of diameter and ocular tonus at 7 mmHg). Functional results: an amelioration of visual acuity was obtained in 5 of 6 cases. CONCLUSION: The anatomic and functional results were satisfactory. Ocular pressure must be normalised before keratoplasty. Important buphtalmia constitutes one contra-indication to this intervention. Hypotonia would appear to be a factor of poor prognosis.

Child↗
PubMed1995

[The cornea of diabetics].

PURPOSE: The aim of the study is to investigate corneal sensitivity and the risk factors of corneal hypoesthaesia in diabetics. METHODS: General examination and full ophthalmologic examination completed by exploration of corneal sensitivity were performed in one hundred thirty diabetic patients. RESULTS: Eleven per cent of patients showed microkystic oedema, whereas corneal hypoesthaesia was found in 45% of cases. Corneal hypoesthaesia was correlated with the duration and balance of diabetic mellitus, the age of patients and the presence of diabetic retinopathy. On the other hand, peripheral neuropathy was found in 88% of cases. CONCLUSION: Ophthalmologic examination of diabetics should not be limited to retina only but should also include the entire eye ball and especially the cornea in patients with high risk.

Adolescent↗
PubMed1993

[Etiologies and risk factors of endophthalmitis].

Endophthalmitis is a serious disease with multiple aetiologies. Its development seems to be dependent upon various risk factors. Among 99 cases of endophthalmitis, 79% were secondary to intraocular surgery especially cataract surgery and perforating ocular trauma. To identify risk factors of post-cataract surgery endophthalmitis, we performed a case-control study: 55 cases and 269 controls were used. Five risk factors were identified: duration of the operative procedure longer than 60 min, suture dehiscence, persistence of lens mass, traumatic cataract and left eye operated. The importance of prevention of endophthalmitis by avoiding such risk factors is raised.

Adolescent↗
PubMed1991

[Epidemiological profile of primary open-angle glaucoma in Tunisia].

The main epidemiologic characteristics of primary angle glaucoma in Tunisia were studied in 5000 patients of Pr. AYED's external consultation at the National Institute of Ophthalmology. It appeared that POAG is a frequent and serious disease in Tunisia: a true problem of public health. The importance of the early diagnosis based essentially on a systematic intraocular pressure test together with the examination of optic disc and the visual field investigation using automated perimetry in suspected cases is discussed.

Adult↗