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Biomedical subjects

L Silva

Publications and source records attributed to L Silva.

At least 55 records · Page 3Linked to original sources
PubMed1989

[The mapping information system: an experience in the development of appropriated software for analysis and presentation of information].

The mapping system (SIMAP), is an experience of the Institute of Nutrition of Central America and Panama in developing an appropriate software (programs) for information needs of the countries of the Central American Isthmus. Through its main characteristics: geographic association, easy use, flexible and versatile, SIMAP is a tool that can easily be used for decision-making in the different sectors. The system's main modules are presented in this article as well as some applications where the SIMAP would serve as support in the analysis and interpretation of information.

Adolescent↗
PubMed1982

Implications for multiple transmitter mediation of amphetamine-induced stereotypies.

Gerbils were pretreated with the dopamine (DA) receptor blocker, pimozide, prior to stereotypy-inducing injections of d-amphetamine. Some of the stereotypies induced with amphetamine were blocked, but some were not, supporting the hypothesis that multiple neurotransmitters are involved in the mediation of amphetamine-induced stereotypy. In addition, when apomorphine hydrochloride was injected, different stereotypic motor behaviors were induced than were induced with amphetamine. The behavioral changes following amphetamine treatment could be classified into four groups: (1) those that are probably DA related, based on the fact that they were induced with either amphetamine or apomorphine, and amphetamine induction was blocked with pimozide; (2) those that are probably not DA related because they were not induced by apomorphine, and amphetamine induction was not blocked by pimozide; (3) those behaviors that may be incompatible with stereotypic behaviors, were reduced with either amphetamine or apomorphine, but were not maintained with pimozide; and (4) circling, which was induced with amphetamine, blocked with pimozide, but not induced with apomorphine.

Animals↗
PubMedDate not supplied

Repair of schistosomal intestinal vascular lesions after curative treatment.

The process of repairing intestinal vascular lesions induced by schistosomiasis in mice was studied before and after curative chemotherapy, by means of histopathology coupled with injections of the mesenteric veins with India ink or plastic, in this case followed by corrosion in strong acid. The granulomas were avascular, mainly formed while within blood vessels, and were associated with distortion of the intestinal vasculature in their proximity, represented by tortuosities, focal dilatation, narrowing, and anastomosis of the mucosal and submucosal veins. Two to four months after cure of schistosomiasis involuting granulomas were seen to be slowly vascularized, a process going from the periphery toward the center of the granulomas. No intravascular granulomas were seen four months after treatment. The previously distorted mucosal and submucosal veins gradually regained their normal appearance, only a slight tortuosity remaining.

Animals↗