Biomedical subjects
Publications and source records attributed to L Sorel.
Intra nodal calcifications associate with breast cancer are uncommon. The rare publications always describe malignant microcaocifications in axillary lymph nodes, evolving with the primary breast tumor imaged on mammography. In the reported observation, we observed calcified metastatic neoplasm in axillary nodes, preceding the intramammary lesion.
Explore the source record for details and available documents.
Neo-electroencephalography (neo-EEG) is a new technique for recording and analyzing brain activity. Mathematical and computerized reconstitution yields a monopolar-like montage. Given the polymorphism of the brain's electrical activity, the computer detects the correct monopolar-like montage for each activity in steps of 0.25 Hz. Conventional EEG detects the difference in potentials between two electrodes. Through the use of monopolar-like montages neo-EEG analysis reveals the amplitude and phase that actually underlie each electrode. The report describes with precision the features of the recording extracts that have been chosen for the analysis, i.e., the number of dominant frequencies, the frequency to the nearest 0.25 Hz and the frequency spectrum for each dominant frequency, then the amplitude to the nearest 0.1 microv and phase shift to the nearest 0.001 sec at each electrode. Some examples of comparisons between neo-EEG and conventional EEG findings are shown and demonstrate the advantages of neo-EEG in detection and differentiation of organic and functional pathologies.
We studied the electrical pattern of spikes and waves and unitemporal foci by compared analysis. One analysis was obtained by two conventional derivations: longitudinal plus triangular and referential to a neck electrode ('vertical derivation'). The other analysis is quantified by the same vertical derivation and by a monopolar-like computerized derivation, the Neo-EEG. With Neo-EEG we obtained a differential dissociation of the spike-and-wave type, and a better analysis of the cerebral dysfunction in temporal foci than in classical EEG. This leads to a sharper diagnosis of the disease it characterizes. This study also shows that one must be aware of the inadequacies and errors resulting from conventional recording because of the bipolar derivations.
Three cases of diffuse subcortical gray matter heterotopias in children are reported. Generalised seizures and mild mental retardation were the most frequent signs. No specific electroencephalographic pattern was recognized. Magnetic resonance imaging scans showed the thick diffuse layer of heterotopic gray matter which was surrounded by normal white matter. Gyration was normal, and no associated malformation was observed. This neuronal migrational disorder happens between the 10th and 16th gestational week. Nineteen observations (17 girls) are reported in the literature. The filiation with agyria-pachygyria and the possible genetic transmission are discussed.
Explore the source record for details and available documents.
A new method of monopolar recording is presented. This true monopolar derivation is based on a computer-reconstituted signals method: use of a reference electrode obtained by interconnecting two electrodes placed one on either side of the neck to form a common pole; detection by Fourier analysis of the various frequencies from 0 to 16 Hz in 1/4 Hz steps; continuous comparison of phase for each activity per 1/4 Hz between the signal PF left - Reference Neck (RC) and O right - Reference Neck (RC) in order to see whether the reference electrode is active or not; automatic subtraction of the value of the reference electrode from the value of all other reference channels if the reference electrode is active. The technique is available for routine purposes. The results are easy to read and provide more precise data as well as new parameters which could prove useful in current clinical practice. The first electroclinical correlations covered frequency, location of potential gradients and phase relations established for 40 adult normal subjects with a reading identified as normal, and for 60 adult pathological subjects with a reading also identified as normal. Clear differences appeared between these two types of supposedly normal readings.
The primary use of lorazepam, when administered intravenously (IV), has been in the treatment of acute attacks of anxiety and agitation. Recent studies have investigated its efficacy in patients with status epilepticus. The present study compared the efficacy and tolerability of lorazepam and clonazepam in the treatment of status epilepticus. Lorazepam, 4 to 10 mg IV, and/or clonazepam, 1 mg IV, was administered in 61 hospitalized epileptic patients. If needed, the dose of each agent was repeated in 20 minutes. Twenty-two patients were given lorazepam, nine were given clonazepam, and 30 were given both drugs at different times. Improvement in EEG was greater with lorazepam while the clinical symptoms responded more completely to clonazepam. Both drugs were most effective in patients with secondary generalized epilepsy. Drowsiness followed either drug. Psychomotor agitation followed either drug in 12% of patients.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.