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Biomedical subjects

L Spitz

Publications and source records attributed to L Spitz.

At least 109 records · Page 6Linked to original sources
PubMed1975

Phaeochromocytoma in childhood. A case report.

The clinical features of a 9-year-old boy with an extra-adrenal phaeochromocytoma, complicated by malignant hypertension, are described. The value of urinary and blood catecholamine assays and specialised radiological investigations in the accurate localisation of the tumour, is emphasised. Successful removal of the tumour was facilitated by pre-operative control of the hypertension with a combination of alpha and beta-adrenergic blockade (phenoxybenzamine and practolol). Intra-operative control of fluctuations in blood pressure was simplified by the use of Ethrane (enflurane compound 347) as one of the anaesthetic agents. As a result, sodium nitroprusside was infrequently used.

Anesthesia, General↗
PubMed1975

Dogbite injuries in children.

An analysis of 50 children suffering from severe dogbites showed that the face was the anatomical site of predilection (75%(, and that the breed of dog most commonly involved was the Alsatian (German Shepherd). Primary debridement and suture under general anaesthesia is the treatment of choice. Ampicillin has been shown to be the antibiotic giving the widest over-all prophylactic chemotherapeutic cover.

Adolescent↗
PubMed1975

Portacaval shunt in four patients with homozygous hypercholesterolaemia.

Four patients with homozygous hyperbetalipoproteinaemia who had proved resistant to intensive medical therapy have undergone portacaval shunt. During 3 weeks of total parenteral alimentation before the operation, the serum-cholesterol decreased significantly in each of the four patients. During the fat-emulsion phase of hyperalimentation, one patient experienced a rise in cholesterol. Postoperatively, the size of xanthomas decreased in all cases; serum-cholesterol levels rose above those achieved during hyperalimentation, and this rise continued for as long as 3 months before a further reduction was recorded. In patients with angina, this improved considerably; and in most cases bruits decreased in itensity. The results at this stage do not, however, suggest portacaval shunt for all patients with homozygous hypercholesterolaemia.

Adolescent↗
PubMed1975

The treatment of neuroblastoma.

A protocol for the management of children with neuroblastoma is described. The appearance of peri-orbital ecchymosis and radiologically demonstrable skeletal metastases are of poor prognostic significance. The relatively infrequent occurrence of neuroblastoma in the Black population of Johannesburg is stressed.

Black or African American↗
PubMed1974

Experience with a cholinesterase histochemical technique for rectal suction biopsies in the diagnosis of Hirschsprung's disease.

Cryostat sections from 160 rectal suction biopsies were stained for cholinesterases by the method of Karnovsky and Roots (1964) in an attempt to facilitate the diagnosis of Hirschsprung's disease. The method proved at least as reliable as experienced assessment of paraffin haematoxylin-eosin sections, and appeared to offer the advantages of reduced scanning fatigue and superior demonstration of the increased cholinesterase-positive nerves in Hirschprung's disease. Contrary to the findings of Meier-Ruge (1971) it was not possible to base a diagnosis on mucosal cholinesterase activity.

Adolescent↗