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L Stables

Publications and source records attributed to L Stables.

2 recordsLinked to original sources
PubMed2006

Measurement of hippocampal subfields and age-related changes with high resolution MRI at 4T.

Histological studies suggest that hippocampal subfields are differently affected by aging and Alzheimer's disease (AD). The aims of this study were: (1) To test if hippocampal subfields can be identified and marked using anatomical landmarks on high resolution MR images obtained on a 4T magnet. (2) To test if age-specific volume changes of subfields can be detected. Forty-two healthy controls (21-85 years) and three AD subjects (76-86 years) were studied with a high resolution T2 weighted fast spin echo sequence. The entorhinal cortex (ERC), subiculum, CA1, CA2 and CA3/4 and dentate were marked. A significant correlation between age and CA1 (r=-0.51, p=0.0002) which was most pronounced in the seventh decade of life was found in healthy controls. In AD subjects, CA1 and subiculum were smaller than in age-matched controls. These preliminary findings suggest that measurement of hippocampal subfields may be helpful to distinguish between normal aging and AD.

Adolescent↗
PubMed1992

Setting nursing standards in hyperbaric oxygen therapy.

This articles focuses on work undertaken as part of a Standards of Care initiative in a Regional Hyperbaric Oxygen Unit in the North of England. The historical development of Hyperbaric Oxygen Therapy, possible clinical applications, and aspects of administration are reviewed. An example of one of the series of nursing standards derived is included together with the patient information sheet and evaluation questionnaire given to patients at the conclusion of the treatment. It is concluded that writing and monitoring Standards of Care can be a very effective quality assurance strategy at unit level.

England↗