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L Stanghellini

Publications and source records attributed to L Stanghellini.

2 recordsLinked to original sources

Large Magellanic Cloud Planetary Nebula Morphology: Probing Stellar Populations and Evolution.

Planetary nebulae (PNe) in the Large Magellanic Cloud (LMC) offer the unique opportunity to study both the population and evolution of low- and intermediate-mass stars, by means of the morphological type of the nebula. Using observations from our LMC PN morphological survey, and including images available in the Hubble Space Telescope Data Archive and published chemical abundances, we find that asymmetry in PNe is strongly correlated with a younger stellar population, as indicated by the abundance of elements that are unaltered by stellar evolution (Ne, Ar, and S). While similar results have been obtained for Galactic PNe, this is the first demonstration of the relationship for extragalactic PNe. We also examine the relation between morphology and abundance of the products of stellar evolution. We found that asymmetric PNe have higher nitrogen and lower carbon abundances than symmetric PNe. Our two main results are broadly consistent with the predictions of stellar evolution if the progenitors of asymmetric PNe have on average larger masses than the progenitors of symmetric PNe. The results bear on the question of formation mechanisms for asymmetric PNe-specifically, that the genesis of PNe structure should relate strongly to the population type, and by inference the mass, of the progenitor star and less strongly on whether the central star is a member of a close binary system.

Journal Article↗

Problems involved in the large scale production of biological products, such as beta-interferon, using diploid fibroblast cells as substrate.

The large-scale and continuous cycle production of Hu beta-IFN serves to indicate that with expansion of cell cultures, aspects such as the reliability of the growth media and the possibility of contamination of cultures may become critical and limiting factors for the production itself. Methods of growth media preparation are described, with particular stress on the problems related to bacterial contamination and water quality. Our production method involves the expansion of cellular cultures using roller bottles, and a final step using the microcarrier technique. The necessity of collecting the cultures in only two fermentors increases the possibilities of contamination. Methods employed in order to minimize these problems are discussed.

Cells, Cultured↗