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L Strada

Publications and source records attributed to L Strada.

31 records · Page 2Linked to original sources
PubMed1981

[Early diagnosis of stomach cancer: report on 23 cases including 15 patients with an acute hemorrhage or perforation (author's transl)].

Early gastric cancer was detected in 23 patients, 15 of whom had acute complications of either hemorrhage or perforation. Cases with acute complications often have a more favorable prognosis as a carcinoma may be identified while still in its pre-invasive stage. The gravity of the complication should not result in the employ of limited diagnostic procedures (e.g. endoscopy without multiple biopsies) or the use of incomplete therapeutic measures (e.g. simple suture of a perforated ulcer). The treatment of hemorrhagic gastric ulcers and perforated ulcers is discussed in greater detail. The need for a continuous follow-up of these patients with gastric ulcers is emphasized. This should include periodic endoscopy examination and multiple biopsies, even when a gastric ulcer has been apparently cured by medical treatment.

Adult↗
PubMedDate not supplied

MR imaging in progressive supranuclear palsy and Shy-Drager syndrome.

Previous reports have suggested that putaminal hypointensity in T2-weighted images at high field strength (1.5 T) magnetic resonance (MR) is a common finding in atypical parkinsonian syndromes, including progressive supranuclear palsy (PSP) and Shy-Drager syndrome (SDS). We have reviewed nine patients with PSP and five with SDS, selected on strict clinical criteria. Only in one PSP patient was abnormal signal intensity (putaminal hypointensity more marked than pallidal) found. However, hypointensity was often marked in the substantia nigra and occasionally in the superior colliculi. Focal midbrain atrophy, involving particularly the upper part of the quadrigeminal plate, was obvious in five cases. In general there was no uniformity of findings and MR appears unable to consistently support the clinical diagnosis of PSP. In SDS patients the findings were more uniform, with hypointensity in the putamen, superior or equal to that of the pallidum. At low or intermediate field strength, there was absence of magnetic susceptibility effect in the putamen, which appeared hyperintense. This was probably because of increased water content due to gliosis and/or cell loss. The constancy of the MR findings in our SDS series suggests a supportive diagnostic role for MR imaging.

Aged↗
PubMedDate not supplied

Cavernous hemangiomas of the orbit: value of CT, angiography, and phlebography.

Neuroradiologic studies performed in 18 cases of surgically verified intraorbital cavernous hemangioma are reported. Skull films usually showed enlargement of the orbit and evidence of soft-tissue mass. Phlebography rarely demonstrated filling of the cavernous hemangioma or enlarged draining veins. On angiography, in addition to displacement of vessels, pooling of contrast medium in the cavities of the hemangioma was observed in more than half the cases. Computed tomography (CT) demonstrated a rounded, hyperdense, enhancing lesion usually in the superior segment of the intraconal space. Although CT may be sufficient for planning the surgical approach, in most cases a combination of CT and angiography will give better, more specific preoperative diagnosis.

Adolescent↗
PubMedDate not supplied

Intracranial cavernous hemangiomas: neuroradiologic review of 36 operated cases.

Neuroradiologic studies in 36 cases of histologically verified intracranial cavernous hemangiomas were reviewed. Radionuclide brain scans were positive in 17 of 19 examinations. Angiography, performed in 35 cases, usually showed an avascular area with absent or moderate mass effect. Capillary blush and/or early draining veins, often mentioned in single case reports, were observed in only seven cases. Computed tomography (18 cases) usually demonstrated a hyperdense, nodular, or irregular lesion without significant mass effect and always enhancing after contrast injection. The combination of a long clinical history of focal epilepsy with computed tomographic and angiographic findings should suggest the diagnosis of cavernous hemangioma. In all cases of so-called spontaneous hematoma with negative angiography, computed tomography should be repeated after a long interval to exclude the presence of a cavernous hemangioma or other cryptic vascular malformation.

Adolescent↗
PubMedDate not supplied

Hallervorden-Spatz disease: MR and pathologic findings.

PURPOSE: To compare the MR findings of eight cases with clinical diagnosis of Hallervorden-Spatz disease (HSD) with the pathologic findings of two other cases of HSD. MATERIALS AND METHODS: The eight imaged cases were studied with 0.5-T (seven cases) and/or 1.5-T (five cases) units. Six patients also had CT scans. The two other cases with proven HSD had detailed histologic evaluation. RESULTS: The 1.5-T findings showed abnormalities confined to the pallidum, which presented a diffuse low signal intensity in T2-weighted images, and an anteromedial area of high signal intensity (eye-of-the-tiger sign). In 0.5-T studies, low signal intensity was less evident and poorly detectable in spin echo, but gradient-echo images could enhance its demonstration; the area of high signal intensity was always well demonstrated. In three cases (three with 1.5 T, one with 0.5 T) a central spot of low signal intensity was seen in this area. The pathologic cases, in addition to neuroaxonal swellings and iron deposits, exhibited areas of "loose" tissue with vacuolization and lesser amounts of iron in the anteromedial part of the pallidum, in a location corresponding to the area of high signal intensity of the imaged cases. CONCLUSION: Comparison of MR findings with the pathologic studies demonstrates that the low signal intensity in T2-weighted images at 1.5 T corresponds to iron deposits in a dense tissue, and that the high signal intensity of the eye-of-the-tiger sign corresponds to an area of loose tissue with vacuolization. No correlation was found in the two pathologic cases for the central spot of low signal intensity.

Adolescent↗