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Biomedical subjects

L Surján

Publications and source records attributed to L Surján.

At least 19 recordsLinked to original sources
PubMed1994

[First experiences with the new financing system and health care plans].

Our experience on the new health reimbursement system and further plans for secondary care. The author gives a short review about the steps of the health reform emphasizing the importance of initiation of performance based reimbursement which has supported to reach the aims of our reform. The results of the new reimbursement system, its practical difficulties, the actions taken to overcome them are also presented. It can be stated that no theoretical objection has been arised against the performance based reimbursement. A committee has been elected for the necessary continuous maintenance of the system. The equalization of the facilities, the reconstruction process of the hospitals, the investments financed by the World Bank loans are the conditions of the further reforms. The program "For the Healthier Nation" is the most important contribution to our health reform. Financially this program based on the "The Health Promotion Foundation".

Health Care Reform↗
PubMed1990

[Unity of diagnostic pathology, continuing education and research at our institute].

Authors give a brief view on the activity in Institute of Pathology and Histopathology of Post-graduate University of Medicine. In its frame, close relation of diagnostic, post-graduate education and research activity is illustrated by examples of different fields (intestinal, cardiac, vascular system, respiratory tract, organ of locomotion, urological diseases, electronmicroscopic tumor diagnostics, endocrinology). Importance of modern morphological methods and their place both in practical and scientific activity are dealt with.

Cardiovascular Diseases↗
PubMed1988

Immunohistochemical markers of tonsillar crypt epithelium.

The crypt epithelium of human palatinal tonsils is a specialized squamous epithelium characterized by the presence of intraepithelial passages which are filled by non-epithelial cells. The passages are covered by the so-called M cells. This reticulated epithelium (reticulum = network) is a highly differentiated one. In the present study immunohistochemical markers were searched for the discrimination between the superficial mucosal squamous epithelium (from which the crypts were developed) and the reticulated crypt epithelium. The reticulated epithelium is replaced by simple squamous epithelium in the course of recurrent tonsillitis. The immunohistochemical characteristics of this metaplastic epithelium were also studied. The superficial epithelium expressed blood group antigens extensively, but these antigens were almost absent from the crypt epithelium. Epithelial membrane antigen was present only in the superficial layers of the surface epithelium. Abundant positivity was characteristic for the reticulated epithelium. The metaplastic foci in the crypts were identical with the surface squamous epithelium using these markers.

ABO Blood-Group System↗
PubMed1984

Jejunoscopic lactose provocation.

A new method for testing lactose intolerance was developed. The examination is performed by jejunoscopy using lactose dilution for provocation and sucrose for control. Macroscopic and microscopic changes in the jejunal mucosa are examined after administration of solutions. The results of this study demonstrated that lactose administration causes prompt change in the jejunal mucosa in cases of lactose intolerance but had no effect in cases of lactose tolerance. Administration of sucrose did not result in any change. This method is effective in proving lactose intolerance and may be useful to elucidate the pathogenesis of this disorder.

Adult↗
PubMed1979

Lymphocyte activation and the increase of nuclear birefringence.

Nuclear birefringence of neutral red or rivanol stained cell suspensions from rat spleen has been investigated. Polyclonal or monoclonal mitogens produced an increased birefringence of the nucleus following 30 min in vitro stimulation at 37 degrees C. The nuclear birefringence increased by 62.2% [p less than 0.001], when the cells were incubated in the supernatants of a previously phytohemaglutinin stimulated culture. Amantadine, a potent phytohemagglutinin inhibitor, was unable to prevent the effect of the supernatant, but heating for 1 h at 56 degrees C destroyed its activity. The results suggest that increase in nuclear birefringence is mediated by a soluble factor which is released in the course of lymphocyte activation. The nuclear birefringence of surviving cells from human spleens obtained within 6 to 24 h post mortem increases after in vitro stimulation.

Animals↗
PubMed1978

[Functional morphology of Peyer's patches. Lymphocyte activation in Peyer's patches].

Peyer plaques of rats were studied by morphological methods in order to compare the structure of these organs with the present theories on their function. It was established that near to the follicules of plaques folds perpendicular to the intestinal passage are formed, which are able to direct a part of the bowel-contents into the direction of the follicules. Between the surface of the follicules and large intestinal villi recesses are formed, in which stagnation of the intestinal content takes place. As a result of this antigens and mitogens containing in the intestinal lumen can contact lymphoid cells of through the special epithelial cells the Peyer-plaques. The latter were recently studied by polarized light too, since earlier studies of the authors have shown that birefringence of these cells depends on their functional state. Authors disclosed that birefringence of the cells of the Peyer-plaques is significantly stronger, than that of the cells of spleen, lymph nodes, and thymus. Cells with increased birefringence are situated on the epithelial side of the capsule of follicules. Reported studies evidence, that Peyer-plaques are structures specialized for incorporation of antigens. Lymphoid cells of Peyer-plaques are activated by effects coming from the intestinal lumen.

Animals↗
PubMed1976

Regulatory hyperparathyroidism: the role of C-cell hyperplasia.

Four cases with clinical and biochemical evidence of hyperparathyroidism are reported. The syndrome was due to DHT-intoxication of iatrogenic origin in the first case to histologically confirmed C-cell hyperplasia of the thyroid in the three others. The collective term "regulatory hyperparathyroidism" is porposed for the syndromes which, in distinction to secondary parathyroidisms, have a pathogenesis other than a negative calcium balance. Management of the syndrome is discussed with particular emphasis on the removal of the TCT-producing hyperplasia or adenoma, and the restoration of the electrolyte balance.

Aged↗