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Biomedical subjects

L Szafraniec

Publications and source records attributed to L Szafraniec.

7 recordsLinked to original sources
PubMed1999

[Examination of the quality of life in post stroke patients].

The clinical assessment of patients after stroke is usually focused on the detection and determination of neurological deficits. However, the full picture of the patient after stroke should take into account also cognitive deficits, emotional and intellectual disturbances as well as limitations in performing one's social functions. Thus, assessing quality of life after stroke is an alternative to traditional methods of evaluation of the patient's condition. The study presents the attempts to define quality of life determined by the health status and to review questionnaires devised for the examination of post-stroke patients. Despite a considerable variety of methods used, reliable evaluation of all the areas of the patients life after stroke seems impossible using only one research tool. There is also an urgent need to develop an uniform system of evaluation, appropriate for Polish cultural standards.

Cerebrovascular Disorders↗
PubMed1999

[Evaluation of quality of life in patients after stroke].

The investigations concerning quality of life after stroke provide an alternative approach in comparison with traditional evaluation of the patient's condition focused only on neurological deficits. The full picture of the patient after stroke should take into account not only locomotor inefficiency, but also cognitive deficits, emotional disturbances and limitations in performing one's social functions. The study present attempts to define health related quality of life and reviews questionnaires devised for the examination of post-stroke patients. Despite a wide variety of methods used, the evaluation of all the areas of the patient's life after stroke seems impossible using only one research tool. There is also an urgent need to develop a uniform system of evaluation, appropriate for Polish cultural standards.

Adaptation, Psychological↗
PubMed1997

[Pathologic laughing and crying in neurologic disorders].

Affective disorders are complications of many nervous system diseases. Pathological laughing and crying may accompany cerebrovascular lesions, multiple sclerosis, ALS, Alzheimer disease or cerebral tumours. Precise mechanisms of how these disorders arise are still unknown. Reviews of the literature were been accomplished in the article where, taking the examples of stroke and multiple sclerosis, have been discussed: the clinic picture, pathogenesis in neuroanatomic and neurophysiologic aspects as well as diagnostic criteria and the treatment of uncontrolled pathological laughing and/or crying.

Crying↗
PubMed1996

[Depression as a complication of stroke].

Depression remains frequent occurrenced (25-60%) but rare detected and treated stroke complication. It may have an essential influence on patients' rehabilitation by delaying their time of health remittance. On the basis of literature review present prevalence, pathogenesis and phenomenology of the poststroke depression. We have also paid attention on so called silent strokes role, which may be cause of depression syndromes occurred at elder and pre-elder people.

Cerebrovascular Disorders↗
PubMed1989

Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry.

Combined use of chemical degradation, derivatization, and tandem mass spectrometry for rapid structural characterization of toxic cyclic peptides from blue-green algae at the nanomole level is described. Previously, all blue-green algal toxins were thought to belong to a family of seven-residue cyclic peptides, having the general structure cyclo-D-Ala-L-Xaa-erythro-beta-methyl-D-isoaspartic acid-L-Yaa-Adda-D-isoglutamic acid-N-methyldehydroalanine, where Xaa and Yaa represent variable amino acids of the L configuration and Adda is 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Structural characterization of two additional toxins indicates that further variability can exist within this family of naturally occurring toxic cyclic peptides. Isoaspartic acid and dehydroalanine can substitute for beta-methylisoaspartic acid and N-methyldehydroalanine, respectively.

Amino Acid Sequence↗