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Biomedical subjects

L Szlávi

Publications and source records attributed to L Szlávi.

4 recordsLinked to original sources

Lymphatic cardiomyopathy: cardiac lymphostasis in the pathogenesis of arrhythmias.

Artificial lymphatic cardiomyopathy was produced in 30 dogs by ligating the regional lymph nodes and the efferent collecting lymph trunks of the heart. In the development of cardiac lymphostasis the appearance of arrhythmias and conduction disturbances was revealed by repeated ECG recordings. The arrhythmic condition of the heart increased and pacemaker function of the sinus node deteriorated in lymphatic cardiomyopathy. Cardiac lymphostasis could be detected during open heart surgical procedure and in long lasting tachycardiac attacks. It is probable that the cardiac lymphostasis has a role in the pathogenesis of some arrhythmias.

Animals↗

Limb circulation in varicosity of various types.

Regulation of limb circulation was studied by the use of the venous isotope dilution technique in 35 patients with leg varicosities. The circulatory parameters of 54 patients with normal limb circulation served as control. The various types of varicosity revealed characteristic circulatory patterns. (i) In the cases of congenital, "juvenile", varicosity limb blood flow is high, the limb AV-O2 difference is very slight and limb O2 uptake is normal. (ii) In secondary varicosity consecutive to thrombophlebitis the limb (total) blood flow is slightly reduced, the limb AV-O2 difference is smaller than normal and O2 uptake by the extremital tissues is diminished. (iii) In non-congenital, primary varicosity, i.e. in the most common form, limb blood flow is normal, the limb vascular resistance is slightly increased. The possibilities of the production of an AV shunt and the clinical implications of the circulatory changes accompanying the various types of varicosity are discussed.

Adult↗

Arteriovenous shunts associated with peripheral obliterative arterial disease. Haemodynamic, arteriographic and isotope studies.

From among 210 patients with severe peripheral obliterative arterial disease, the presence of an arteriovenous shunt was demonstrated in 17 cases. Arteriovenous communications were visualized by serial angiographic records and 99mTc macroaggregate isotope testing. The regulation of the limb circulation was investigated using the venous isotope dilution method. Characteristic haemodynamic changes were revealed in arteriovenous shunts associated with peripheral arterial obliterative disease: total limb blood was comparatively high, arteriovenous difference was low and limb O2 consumption was decreased. The clinical significance of the haemodynamic changes in arteriovenous shunting associated with obliterative arterial disease is discussed.

Adult↗