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Biomedical subjects

L T Kashintseva

Publications and source records attributed to L T Kashintseva.

At least 19 recordsLinked to original sources
PubMed1990

[The effect of a pulsed electromagnetic field on the hemodynamics of eyes with glaucoma].

The influence of pulse electromagnetic field (PEMF) on hemodynamics of the eye in open-angle glaucoma has been studied by means of a method and a device proposed at the Filatov Institute. The PEMF characteristics are: impulse frequency--50 Hz, exposition--0,02 sec., impulse shape--square, rate of impulse rise--4.10(4) c rate of magnetic induction rise--2.10(4) mT/c, amplitude value of magnetic induction at the impulse height--9.0--8.5 mT, duration of the procedure--7 min., a course--10 sessions. Observations over 150 patients (283 eyes) with latent, initial and advanced glaucoma have shown a positive influence of PEMF on hemodynamics of a glaucomatous eye: a rise of rheographic coefficient and relative volume pulse in 87,99 and 81,63%, respectively. The degree of the rise and restoration frequency of rheographic values of the glaucomatous eye under the influence of PEMF to the age norm was more expressed at initial stages of the glaucomatous process (latent and initial glaucoma).

Aged↗
PubMed1990

[One-stage extracapsular cataract extraction with sinusotrabeculotomy in patients with combined glaucoma and cataract].

The paper deals with the question about surgical treatment of patients with glaucoma associated with cataract. A new technique of one-stage extracapsular cataract extraction with sinusotrabeculotomy is proposed. Its main point is a change in the sequence of stages: stage I--opening of anterior lens capsule, stage II--antiglaucomatous operation, stage III--extraction of lenticular nucleus and masses through a corneal incision. The operation was made in 30 patients (31 ages). The follow-up period was 2 years. Normalization of intraocular pressure was achieved in all patients, in one eye--miotics had to be used. All patients showed a rise of visual functions: in 21 of 31 eyes vision rose to 0.3 and higher. In one patient vision fell after a year because of progression of the glaucomatous process in the presence of normal intraocular pressure. One-stage extracapsular cataract extraction with sinusotrabeculotomy can be made at any stage of glaucoma. By the authors' data, contraindications can be a rise of intraocular pressure above 40.0 mm Hg as well as the presence of a single eye and severe course of hypertonic disease.

Cataract Extraction↗
PubMed1990

[Late observations on the effectiveness of a new antiglaucoma operation--"concealed" sinusotrabeculotomy--in initial exfoliative glaucoma].

The paper describes results after surgical treatment of patients with initial exfoliative glaucoma in 150 eyes. Of them, sinusotrabeculectomy (STET) was made in 49 eyes, sinusotrabeculotomy (STT)--in 50, a new, proposed by the authors, operation--a "cap peak" sinusotrabeculotomy (CPSTT)--in 66 eyes; the latter excludes direct fistulization of the anterior chamber under the superficial scleral flap. It is noted that CPSTT at initial exfoliative stage of glaucoma leads to a remarkably lower incidence of complications at the time of operation and early postoperative period. Hyphema and anterior chamber emptying were recorded at the time of STET in 22.4% and 16.3%, of STT--in 8.0% and 10.0%, while at the time of CPSTT--only in 3.0% and 1.5%, respectively. Iridocyclitis, flat anterior chamber and detachment of the choroid were observed after STET in 32.6%, 24.5% and 26.5%, after STT--in 22.0%, 14.0% and 16.0%, and after CPSTT--in 6.0%, 4.5% and 1.5%, respectively. In remote terms (3 years after the operations), stabilization of visual acuity and visual field was recorded after STET in 69.3% and 85.7%, after STT--in 82.0% and 90.0%, and after CPSTT--in 87.9% and 92.4%, respectively. Stable normalization of intraocular pressure took place after STET in 93.8%, after STT--in 98.0%, and after CPSTT--in 96.9%. After STET and STT, hypotony was recorded in 28.5% and 18.0%, respectively, and after CPSTT--in none of the cases. The operation of a "cap peak" sinusotrabeculotomy is proposed as an operation of choice for treatment of exfoliative and common open-angle glaucomas in persons above 65 years of age.

Aged↗
PubMed1990

[A comparative assessment of the effectiveness of sinusotrabeculotomy in different stages of open-angle glaucoma].

The paper analyses immediate and remote (to 4.5 years) results after sinusotrabeculotomy in 233 patients (244 eyes) with open-angle glaucoma. Among 244 eyes, 93 had initial, 87--advanced, and 64--far-advanced stages of glaucoma. It is recorded that such postoperative complications, as detachment of the choroid and hypotony, appear rarer in initial (12.5% and 15.0%, respectively), than in far-advanced (18.7% and 20.3%, respectively) stage of glaucoma. In remote terms after operation, the incidence of visual acuity and visual field preservation is higher in initial (92.5% and 95.7%, respectively), than in advanced (78.2% and 87.4%), and, in particular, far-advanced (70.3% and 79.7%) stages of the disease. After surgery at initial stage of glaucoma, restoration of tonographic values is more expressed (C = 0.24 +/- 0.004, F = 2.1 +/- 0.03), than at advanced (C = 0.23 +/- 0.007, F = 1.8 +/- 0.06) and far-advanced (C = 0.19 +/- 0.005, F = 1.1 +/- 0.04) stages. It is emphasized that in order to achieve the highest effectiveness of surgical treatment at the initial stage of open-angle glaucoma, the ophthalmic surgeon should be highly skilled in this field of surgical treatment of such patients.

Adult↗
PubMed1989

[Late results of transscleral hypotensive low-energy laser therapy of glaucoma].

The paper discusses remote observations (within 5 years) over 64 patients (94 eyes) with open-angle glaucoma after transscleral hypotensive low-energy laser therapy. Before treatment, intraocular pressure was moderately increased in 63 eyes (67%), high--in 31 (33%). In 27 eyes with minimum, moderately expressed dystrophic changes in the anterior segment of the eye, a course of transscleral hypotensive low-energy laser therapy, 1-2 sessions, resulted in normalization of intraocular pressure and improvement of hydrodynamics, remaining stable within the whole period of observation. In 49 eyes with moderately expressed dystrophic changes in the anterior segment of the eye, a course of 3-5 sessions brought about normalization of intraocular pressure, remaining stable within 6-12 months, on the average. In 18 eyes with strongly expressed dystrophic changes in the anterior segment of the eye, a partial hypotensive effect was achieved and the patients were operated a month later. In patients with a normalized intraocular pressure, stabilization of visual functions (visual acuity and visual field) within the whole period of observation is also recorded.

Follow-Up Studies↗
PubMed1988

[Cyclic nucleotides in experimental glaucoma].

cAMP and cGMP contents were studied in various eye tissues of rabbits with experimental glaucoma induced by chronic intravenous adrenaline administration. Cyclic nucleotide level was measured in the retina, choroid, iris and ciliary body. An increase in the tissue cAMP level was found especially in the iris and ciliary body. An increase in tissue cAMP content is explained by an enhanced beta-adrenergic regulation in the eyes of rabbits with experimental glaucoma. No consistent changes were found in cGMP content in eye tissues.

Animals↗